The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice. (Q41823871)

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scientific article published on October 1999

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English	The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice.	scientific article published on October 1999

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scholarly article

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1 November 2019

The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice (English)

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1 November 2019

blood–brain barrier

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based on heuristic

inferred from title

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inferred from title

Elizabeth C de Lange

4

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1 November 2019

author name string

R Xie

1

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1 November 2019

M Hammarlund-Udenaes

2

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1 November 2019

A G de Boer

3

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1 November 2019

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publication date

1 October 1999

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1 November 2019

British Journal of Pharmacology

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128

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1 November 2019

3

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1 November 2019

563-568

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1 November 2019

BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123.

1 reference

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6 June 2018

Blood-brain barrier equilibration of codeine in rats studied with microdialysis.

1 reference

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6 June 2018

Application of microdialysis in pharmacokinetic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Quantitative microdialysis under transient conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

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6 June 2018

Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression.

1 reference

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6 June 2018

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Blood-Brain Barrier: Penetration of Morphine, Codeine, Heroin, and Methadone after Carotid Injection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Studies on the transport of morphine into the cerebrospinal fluid of rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Isolation and expression of a complementary DNA that confers multidrug resistance

1 reference

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6 June 2018

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Species difference of site-selective glucuronidation of morphine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Pharmacokinetics of morphine in plasma and discrete areas of the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

6 June 2018

Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

18 August 2018

Effect of the Mdr1a P-glycoprotein gene disruption on the tissue distribution of SDZ PSC 833, a multidrug resistance-reversing agent, in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

18 August 2018

Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

18 August 2018

Relationship between analgesia and extracellular morphine in brain and spinal cord in awake rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

18 August 2018

Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571655

18 August 2018

Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of effect delay and acute tolerance development to morphine in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and cerebrospinal fluid concentrations of morphine and morphine glucuronides in rabbits receiving single and repeated doses of morphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug equilibration across the blood-brain barrier--pharmacokinetic considerations based on the microdialysis method

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/10516633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0702804

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10516633%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10516633%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Europe PubMed Central

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1 November 2019

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