HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion (Q41834933)

12 October 2017

HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion (English)

1 reference

12 October 2017

1 reference

4

Erwin Bottinger

1 reference

12 October 2017

Kristina E Hoot

1

1 reference

12 October 2017

Masako Oka

2

1 reference

12 October 2017

Gangwen Han

3

1 reference

12 October 2017

Qinghong Zhang

5

1 reference

12 October 2017

Xiao-Jing Wang

6

1 reference

12 October 2017

language of work or name

English

0 references

publication date

13 September 2010

1 reference

Journal of Clinical Investigation

12 October 2017

1 reference

12 October 2017

120

1 reference

12 October 2017

10

1 reference

12 October 2017

3606-3616

1 reference

describes a project that uses

12 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2947237/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

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Epidermal Smad4 deletion results in aberrant wound healing

6 June 2018

1 reference

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Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation

6 June 2018

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Modes of resistance to anti-angiogenic therapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Identification of the gene transcription and apoptosis mediated by TGF-beta-Smad2/3-Smad4 signaling

6 June 2018

1 reference

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The MET receptor tyrosine kinase in invasion and metastasis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Hepatocyte growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

6 June 2018

1 reference

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Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

6 June 2018

1 reference

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The logic of TGFbeta signaling.

6 June 2018

1 reference

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Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation

6 June 2018

1 reference

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Smad transcription factors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin

6 June 2018

1 reference

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Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

TGF-beta receptor function in the endothelium.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Smad3 mediates TGF-beta1 induction of VEGF production in lung fibroblasts.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

6 June 2018

1 reference

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Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model

6 June 2018

1 reference

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Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

A Smad transcriptional corepressor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Transforming growth factor-beta selectively inhibits branching morphogenesis but not tubulogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Structural and functional characterization of the mouse hepatocyte growth factor gene promoter.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947237

TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20852387

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Generation of Smad4/Dpc4 conditional knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20852387

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI43304

1 reference

12 October 2017

1 reference

12 October 2017

1 reference