Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy. (Q41850603)

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13 October 2019

title

Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy (English)

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13 October 2019

3

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13 October 2019

author name string

D J King

1

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13 October 2019

P Antoniw

2

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13 October 2019

J R Adair

4

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13 October 2019

A M Haines

5

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13 October 2019

A P Farnsworth

6

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13 October 2019

H Finney

7

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13 October 2019

A D Lawson

8

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13 October 2019

A Lyons

9

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13 October 2019

T S Baker

10

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13 October 2019

language of work or name

English

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publication date

1 December 1995

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British Journal of Cancer

13 October 2019

published in

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13 October 2019

volume

72

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13 October 2019

issue

6

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13 October 2019

page(s)

1364-1372

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Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer

13 October 2019

cites work

1 reference

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Comparative biodistributions of indium-111-labelled macrocycle chimeric B72.3 antibody conjugates in tumour-bearing mice

5 June 2018

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The construction of a highly efficient and versatile set of mammalian expression vectors.

5 June 2018

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Mouse/human chimeric monoclonal antibody in man: kinetics and immune response

5 June 2018

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Yttrium-90-labeled monoclonal antibody for therapy: labeling by a new macrocyclic bifunctional chelating agent

5 June 2018

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Quantitative analysis of antibody localization in human metastatic colon cancer: a phase I study of monoclonal antibody A33.

5 June 2018

1 reference

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Biodistribution and radiation dose estimates for yttrium- and iodine-labeled monoclonal antibody IgG and fragments in nude mice bearing human colonic tumor xenografts

5 June 2018

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Determination of affinities of murine and chimeric anti alpha/beta-T-cell receptor antibodies by flow cytometry

5 June 2018

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Humanized antibodies for antiviral therapy

5 June 2018

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Choosing the Right Radionuclide and Antibody for Intraperitoneal Radioimmunotherapy

5 June 2018

1 reference

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Expression, purification and characterization of a mouse-human chimeric antibody and chimeric Fab' fragment

5 June 2018

1 reference

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Polymerase chain reaction facilitates the cloning, CDRgrafting, and rapid expression of a murine monoclonal antibody directed against the CD18 component of leukocyte integrins

5 June 2018

1 reference

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Human antibody effector function

5 June 2018

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High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification

5 June 2018

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High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker

5 June 2018

1 reference

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Comparative toxicity studies of yttrium-90 MX-DTPA and 2-IT-BAD conjugated monoclonal antibody (BrE-3).

5 June 2018

1 reference

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Calculated beta-ray dose factors for trabecular bone

18 August 2018

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12 December 2020

Improved tumor targeting with chemically cross-linked recombinant antibody fragments

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12 December 2020

Patient biodistribution of intraperitoneally administered yttrium-90-labeled antibody

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12 December 2020

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

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12 December 2020

Expression in COS cells of a mouse-human chimaeric B72.3 antibody

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12 December 2020

Intraperitoneal yttrium-90-labeled monoclonal antibody in ovarian cancer

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12 December 2020

Rapid PCR-cloning of full-length mouse immunoglobulin variable regions

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12 December 2020

Reduced immunogenicity and improved pharmacokinetics of humanized anti-Tac in cynomolgus monkeys

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12 December 2020

The in vivo release of 90Y from cyclic and acyclic ligand-antibody conjugates

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12 December 2020

Development of humoral immune responses against a macrocyclic chelating agent (DOTA) in cancer patients receiving radioimmunoconjugates for imaging and therapy

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12 December 2020

Humanised monoclonal antibody therapy for rheumatoid arthritis

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12 December 2020

Biological and immunological features of humanized M195 (anti-CD33) monoclonal antibodies

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12 December 2020

Engineering antibodies for therapy

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12 December 2020

Immunogenicity in rabbits and mice of an antibody-chelate conjugate: comparison of (S) and (R) macrocyclic enantiomers and an acyclic chelating agent

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12 December 2020

Pharmacokinetics of the monoclonal antibody B72.3 and its fragments labeled with either 125I or 111In

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12 December 2020

Identifiers

DOI

10.1038/BJC.1995.516

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8519646%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

1 reference

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13 October 2019

PubMed publication ID

8519646

1 reference