MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells (Q41871901)

13 October 2017

MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells (English)

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13 October 2017

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11

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13 October 2017

2

Agnieszka Bronisz

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13 October 2017

13

Jakub Godlewski

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13 October 2017

Pierpaolo Peruzzi

1

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13 October 2017

Michal O Nowicki

3

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13 October 2017

Yan Wang

4

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13 October 2017

Daisuke Ogawa

5

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13 October 2017

Richard Price

6

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13 October 2017

Ichiro Nakano

7

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13 October 2017

Chang-Hyuk Kwon

8

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13 October 2017

Josie Hayes

9

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13 October 2017

Sean E Lawler

10

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13 October 2017

E Antonio Chiocca

12

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13 October 2017

3 June 2013

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13 October 2017

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13 October 2017

15

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13 October 2017

9

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13 October 2017

1212-1224

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describes a project that uses

13 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3748913/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Brain cancer stem cells: current status on glioblastoma multiforme

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Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells

5 June 2018

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Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy

5 June 2018

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PRC2 during vertebrate organogenesis: a complex in transition

5 June 2018

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miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis

5 June 2018

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Malignant glioma: lessons from genomics, mouse models, and stem cells

5 June 2018

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MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1.

5 June 2018

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MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

5 June 2018

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Glioblastoma cancer stem-like cells: implications for pathogenesis and treatment

5 June 2018

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5 June 2018

Stem cells in gliomas.

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Bmi-1 induces radioresistance in MCF-7 mammary carcinoma cells

5 June 2018

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MicroRNAs in the pathogenesis of cancer

5 June 2018

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Chemoresistance of glioblastoma cancer stem cells--much more complex than expected

5 June 2018

1 reference

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Epithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connection

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Roles of the Polycomb group proteins in stem cells and cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.

5 June 2018

1 reference

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

5 June 2018

1 reference

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Neural stem cells and glioma stem-like cells respond differently to chemotherapeutic drugs: selectivity at the cellular level

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Polycomb proteins in mammalian cell differentiation and plasticity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway

5 June 2018

1 reference

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MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications

5 June 2018

1 reference

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BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness".

5 June 2018

1 reference

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The Polycomb complex PRC2 and its mark in life

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Polycomb repressive complex 2 in embryonic stem cells: an overview

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and in glioma stem-like cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Clinical significance of Polycomb gene expression in brain tumors.

5 June 2018

1 reference

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Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

The promise of microRNA replacement therapy

5 June 2018

1 reference

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Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

5 June 2018

1 reference

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Polycomb complexes act redundantly to repress genomic repeats and genes

5 June 2018

1 reference

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Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

EZH2 is essential for glioblastoma cancer stem cell maintenance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

BMI1 sustains human glioblastoma multiforme stem cell renewal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

MicroRNAs and glioblastoma; the stem cell connection

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Emerging functions of microRNAs in glioblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

MicroRNAs: target recognition and regulatory functions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Pten haploinsufficiency accelerates formation of high-grade astrocytomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Extensive modulation of a set of microRNAs in primary glioblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Regulation of miRNA expression during neural cell specification

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Identification of human brain tumour initiating cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Identification of a cancer stem cell in human brain tumors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Current epidemiological trends and surveillance issues in brain tumors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

MiR-34 and SNAIL: another double-negative feedback loop controlling cellular plasticity/EMT governed by p53.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Copy number alterations of the polycomb gene BMI1 in gliomas

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Polycomb group proteins in cell cycle progression and cancer.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748913

2 December 2018

Identifiers

DOI

10.1093/NEUONC/NOT055

1 reference

13 October 2017

1 reference

13 October 2017

1 reference