Transcriptional regulation of CXCR4 in prostate cancer: significance of TMPRSS2-ERG fusions (Q41889452)

13 October 2017

Transcriptional regulation of CXCR4 in prostate cancer (English)

1 reference

13 October 2017

significance of TMPRSS2-ERG fusions (English)

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author

M. Katie Conley-LaComb

3

object named as

M Katie Conley-Lacomb

1 reference

13 October 2017

Rajareddy Singareddy

1

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13 October 2017

Louie Semaan

2

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13 October 2017

Jason St John

4

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13 October 2017

Katelyn Powell

5

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13 October 2017

Matthew Iyer

6

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13 October 2017

Daryn Smith

7

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13 October 2017

Lance K Heilbrun

8

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13 October 2017

Dongping Shi

9

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13 October 2017

Wael Sakr

10

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13 October 2017

Michael L Cher

11

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13 October 2017

Sreenivasa R Chinni

12

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13 October 2017

5 August 2013

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Molecular Cancer Research

13 October 2017

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13 October 2017

11

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13 October 2017

11

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13 October 2017

1349-1361

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EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

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1 reference

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1 reference

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1 reference

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5 June 2018

1 reference

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ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

5 June 2018

1 reference

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1 reference

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Androgens Induce Functional CXCR4 through ERG Factor Expression in TMPRSS2-ERG Fusion-Positive Prostate Cancer Cells

5 June 2018

1 reference

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An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

5 June 2018

1 reference

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ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

5 June 2018

1 reference

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Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro

5 June 2018

1 reference

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Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

5 June 2018

1 reference

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

5 June 2018

1 reference

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Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

5 June 2018

1 reference

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A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

5 June 2018

1 reference

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Delineation of TMPRSS2-ERG splice variants in prostate cancer

5 June 2018

1 reference

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Recurrent gene fusions in prostate cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone

5 June 2018

1 reference

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Role of the TMPRSS2-ERG gene fusion in prostate cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

A causal role for ERG in neoplastic transformation of prostate epithelium.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression.

5 June 2018

1 reference

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Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation

5 June 2018

1 reference

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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.

5 June 2018

1 reference

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The importance of the CXCL12-CXCR4 chemokine ligand-receptor interaction in prostate cancer metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration

5 June 2018

1 reference

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Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox

5 June 2018

1 reference

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Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

5 June 2018

1 reference

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CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion

5 June 2018

1 reference

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Interaction of ligand-receptor system between stromal-cell-derived factor-1 and CXC chemokine receptor 4 in human prostate cancer: a possible predictor of metastasis

5 June 2018

1 reference

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Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

5 June 2018

1 reference

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Regulation of the chemokine receptor CXCR4 by hypoxia

5 June 2018

1 reference

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

5 June 2018

1 reference

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Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

5 June 2018

1 reference

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A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Characterization of the DNA binding and transcriptional activation domains of the erg protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer

5 June 2018

1 reference

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Tumor immunobiological differences in prostate cancer between African-American and European-American men.

5 June 2018

1 reference

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pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma.

18 August 2018

1 reference

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Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.

18 August 2018

1 reference

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TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

18 August 2018

1 reference

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Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

18 August 2018

1 reference

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Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas

18 August 2018

1 reference

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Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901058

Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

18 August 2018

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12 December 2020

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

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12 December 2020

The ETS-domain transcription factor family

1 reference

12 December 2020

Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex

1 reference

12 December 2020

Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone

1 reference

12 December 2020

10.1158/1541-7786.MCR-12-0705

Identifiers

DOI

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

23918819

1 reference