Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells. (Q41895046)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15678086%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells (English)

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7 January 2020

3

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7 January 2020

author name string

María A Hidalgo

1

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7 January 2020

Alex Romero

2

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7 January 2020

Patricia Cortés

4

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7 January 2020

Ilona I Concha

5

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7 January 2020

Juan L Hancke

6

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7 January 2020

Rafael A Burgos

7

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7 January 2020

language of work or name

English

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publication date

1 March 2005

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British Journal of Pharmacology

7 January 2020

published in

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7 January 2020

volume

144

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7 January 2020

issue

5

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7 January 2020

page(s)

680-686

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Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration

7 January 2020

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Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50.

5 June 2018

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DRF 3188 a novel semi-synthetic analog of andrographolide: cellular response to MCF 7 breast cancer cells

5 June 2018

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Determination of specific receptor sites for platelet activating factor in bovine neutrophils

5 June 2018

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Anticancer and immunostimulatory compounds from Andrographis paniculata

5 June 2018

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Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy

5 June 2018

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Signal transduction via the NF-kappaB pathway: a targeted treatment modality for infection, inflammation and repair

5 June 2018

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5 June 2018

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Platelet-activating factor increases pH(i) in bovine neutrophils through the PI3K-ERK1/2 pathway

5 June 2018

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Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5'-monophosphate (cAMP)-dependent pathways: involvement of NF-kappa B, activator protein 1, and cAMP response el

5 June 2018

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Natural products as targeted modulators of the nuclear factor-kappaB pathway

5 June 2018

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Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect

5 June 2018

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Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

5 June 2018

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NF-kappaB: a key role in inflammatory diseases

5 June 2018

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Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells by andrographolide

5 June 2018

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Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

5 June 2018

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The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

5 June 2018

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Regulation of intercellular adhesion molecule-1 (CD54) gene expression

5 June 2018

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Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils

5 June 2018

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5 June 2018

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Andrographolide suppresses the expression of inducible nitric oxide synthase in macrophage and restores the vasoconstriction in rat aorta treated with lipopolysaccharide

5 June 2018

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

5 June 2018

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Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway

5 June 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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18 August 2018

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Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway

18 August 2018

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18 August 2018

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18 August 2018

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NF-kappa B regulation in human neutrophils by nuclear I kappa B alpha: correlation to apoptosis

18 August 2018

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Effects of platelet activating factor, butyrate and interleukin-6 on cyclooxygenase-2 expression in human esophageal cancer cells

18 August 2018

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Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes

18 August 2018

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Expression of cyclooxygenase-2 in human neutrophils activated by Helicobacter pylori water-soluble proteins: possible involvement of NF-kappaB and MAP kinase signaling pathway

18 August 2018

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Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2.

18 August 2018

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Experimental autoimmune encephalomyelitis in NF-kappa B-deficient mice:roles of NF-kappa B in the activation and differentiation of autoreactive T cells.

18 August 2018

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Andrographolide protects rat hepatocytes against paracetamol-induced damage.

18 August 2018

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Inhibition of NF-kappaB by mutant IkappaBalpha enhances TNF-alpha-induced apoptosis in HL-60 cells by controlling bcl-xL expression

18 August 2018

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12 December 2020

Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils

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12 December 2020

Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils

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12 December 2020

Expression of genes involved in initiation, regulation, and execution of apoptosis in human neutrophils and during neutrophil differentiation of HL-60 cells

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12 December 2020

Suppression of rat neutrophil reactive oxygen species production and adhesion by the diterpenoid lactone andrographolide

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NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15678086%20AND%20SRC:MED&resulttype=core&format=json

release_ctmx6o2q25f5rfxpw3yh7a74zy

7 January 2020

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24 November 2022

mapped directly with Wikidata item

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7 January 2020

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