Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA (Q41898874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489888%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA (English)

1 reference

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7 March 2020

5

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7 March 2020

Elisabet Englund

9

1 reference

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7 March 2020

Enming Zhang

13

1 reference

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7 March 2020

author name string

Dongfeng Chen

1

1 reference

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7 March 2020

Duo Zuo

2

1 reference

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7 March 2020

Cheng Luan

3

1 reference

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7 March 2020

Min Liu

4

1 reference

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7 March 2020

Liang Ran

6

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7 March 2020

Yingyu Sun

7

1 reference

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7 March 2020

Annette Persson

8

1 reference

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7 March 2020

Leif G Salford

10

1 reference

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7 March 2020

Erik Renström

11

1 reference

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7 March 2020

Xiaolong Fan

12

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7 March 2020

language of work or name

English

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publication date

29 January 2014

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7 March 2020

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7 March 2020

volume

9

1 reference

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7 March 2020

issue

1

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7 March 2020

page(s)

e87281

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Creative Commons Attribution 4.0 International

7 March 2020

copyright license

start time

29 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3906156/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Essential role for endocytosis in the growth factor-stimulated activation of ERK1/2 in endothelial cells.

5 June 2018

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A simplified approach for the molecular classification of glioblastomas

5 June 2018

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The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector

5 June 2018

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Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

5 June 2018

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Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

5 June 2018

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Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling

5 June 2018

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Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles

5 June 2018

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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

5 June 2018

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CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells

5 June 2018

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Molecular subclassification of diffuse gliomas: seeing order in the chaos

5 June 2018

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PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

5 June 2018

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Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

5 June 2018

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

5 June 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation

5 June 2018

1 reference

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Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

5 June 2018

1 reference

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Endosomes: a legitimate platform for the signaling train

5 June 2018

1 reference

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Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.

5 June 2018

1 reference

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Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny.

5 June 2018

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Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells

5 June 2018

1 reference

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

5 June 2018

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An integrated genomic analysis of human glioblastoma multiforme

5 June 2018

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Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis

5 June 2018

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Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

5 June 2018

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Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade

5 June 2018

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

5 June 2018

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5 June 2018

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

5 June 2018

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Dynasore, a cell-permeable inhibitor of dynamin

5 June 2018

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Harnessing actin dynamics for clathrin-mediated endocytosis

5 June 2018

1 reference

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Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes

5 June 2018

1 reference

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Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation

5 June 2018

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Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas

5 June 2018

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Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

5 June 2018

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

5 June 2018

1 reference

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Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis

5 June 2018

1 reference

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5 June 2018

1 reference

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Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Gliomagenesis: genetic alterations and mouse models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

PDGFRα expression distinguishes GFAP-expressing neural stem cells from PDGF-responsive neural precursors in the adult periventricular area.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Blockade of the extracellular signal-regulated kinase pathway enhances the therapeutic efficacy of microtubule-destabilizing agents in human tumor xenograft models

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

PDGF stimulates the massive expansion of glial progenitors in the neonatal forebrain

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

BAC array CGH distinguishes mutually exclusive alterations that define clinicogenetic subtypes of gliomas.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Loss of heterozygosity 1p36 and 19q13 is a prognostic factor for overall survival in patients with diffuse WHO grade 2 gliomas treated without chemotherapy

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Glial progenitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

A human brain tumor-derived PDGFR-alpha deletion mutant is transforming

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906156

10.1371/JOURNAL.PONE.0087281

18 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489888%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489888%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

24489888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489888%20AND%20SRC:MED&resulttype=core&format=json