Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. (Q41909132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348724%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein (English)

1 reference

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4 January 2020

6

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4 January 2020

Carmela R Abraham

8

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4 January 2020

author name string

Celina V Zerbinatti

1

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4 January 2020

Joanna M Cordy

2

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4 January 2020

Ci-Di Chen

3

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4 January 2020

Maria Guillily

4

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4 January 2020

Sokreine Suon

5

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4 January 2020

Guy R Seabrook

7

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4 January 2020

Benjamin Wolozin

9

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4 January 2020

publication date

18 March 2008

1 reference

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Molecular Neurodegeneration

4 January 2020

published in

1 reference

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4 January 2020

volume

3

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4 January 2020

page(s)

5

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https://scigraph.springernature.com/pub.10.1186/1750-1326-3-5

4 January 2020

exact match

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323375

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323375

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

5 June 2018

1 reference

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

5 June 2018

1 reference

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

5 June 2018

1 reference

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5 June 2018

1 reference

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Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides

5 June 2018

1 reference

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Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

5 June 2018

1 reference

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Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

5 June 2018

1 reference

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Amyloid precursor protein interacts with notch receptors

5 June 2018

1 reference

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Overexpression of OSBP-related protein 2 (ORP2) induces changes in cellular cholesterol metabolism and enhances endocytosis.

5 June 2018

1 reference

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OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation

5 June 2018

1 reference

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The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

5 June 2018

1 reference

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Differential expression of cholesterol hydroxylases in Alzheimer's disease

5 June 2018

1 reference

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Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

5 June 2018

1 reference

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Surface expression of inward rectifier potassium channels is controlled by selective Golgi export

5 June 2018

1 reference

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5 June 2018

1 reference

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

5 June 2018

1 reference

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Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum.

5 June 2018

1 reference

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Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

5 June 2018

1 reference

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Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis

5 June 2018

1 reference

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5 June 2018

1 reference

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A fluid connection: cholesterol and Abeta

5 June 2018

1 reference

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Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323375

Oxysterol biosynthetic enzymes

5 June 2018

1 reference

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Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

5 June 2018

1 reference

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

5 June 2018

1 reference

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Family of human oxysterol binding protein (OSBP) homologues. A novel member implicated in brain sterol metabolism

5 June 2018

1 reference

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

5 June 2018

1 reference

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Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein

5 June 2018

1 reference

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The role of cholesterol in the biosynthesis of beta-amyloid

5 June 2018

1 reference

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5 June 2018

1 reference

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1 reference

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5 June 2018

1 reference

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Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol

5 June 2018

1 reference

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5 June 2018

1 reference

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

5 June 2018

1 reference

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5 June 2018

1 reference

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5 June 2018

1 reference

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5 June 2018

1 reference

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Purification of oxysterol binding protein from hamster liver cytosol

5 June 2018

1 reference

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Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding

5 June 2018

1 reference

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Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

5 June 2018

1 reference

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5 June 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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18 August 2018

1 reference

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Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain

18 August 2018

1 reference

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18 August 2018

1 reference

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Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18348724

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1750-1326-3-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348724%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348724%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference