Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production (Q41911438)

14 October 2017

Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production (English)

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14 October 2017

José Luis Vela

1

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14 October 2017

Djemel Aït-Azzouzene

2

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14 October 2017

Bao Hoa Duong

3

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14 October 2017

Takayuki Ota

4

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14 October 2017

David Nemazee

5

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14 October 2017

language of work or name

English

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publication date

7 February 2008

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14 October 2017

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14 October 2017

28

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14 October 2017

2

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14 October 2017

161-170

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describes a project that uses

14 October 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2351955/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Igkappa allelic inclusion is a consequence of receptor editing

5 June 2018

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Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

5 June 2018

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A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes.

5 June 2018

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Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

5 June 2018

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An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

5 June 2018

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Tracing the pre-B to immature B cell transition in human leukemia cells reveals a coordinated sequence of primary and secondary IGK gene rearrangement, IGK deletion, and IGL gene rearrangement

5 June 2018

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Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

5 June 2018

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Editing anti-DNA B cells by Vlambdax

5 June 2018

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Regulation of anti-DNA B cells in recombination-activating gene-deficient mice

5 June 2018

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Receptor editing occurs frequently during normal B cell development.

5 June 2018

1 reference

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

5 June 2018

1 reference

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Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells

5 June 2018

1 reference

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Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition

5 June 2018

1 reference

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B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

5 June 2018

1 reference

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Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

5 June 2018

1 reference

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Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans

5 June 2018

1 reference

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Receptor editing in self-reactive bone marrow B cells

5 June 2018

1 reference

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B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

5 June 2018

1 reference

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Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa

5 June 2018

1 reference

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Unusual patterns of immunoglobulin gene rearrangement and expression during human B cell ontogeny: human B cells can simultaneously express cell surface kappa and lambda light chains

5 June 2018

1 reference

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Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

5 June 2018

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kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire

5 June 2018

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The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa

5 June 2018

1 reference

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Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Deletions of kappa chain constant region genes in mouse lambda chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

A uniform deleting element mediates the loss of kappa genes in human B cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

How immunoglobulin V kappa genes rearrange

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

The human kappa deleting element and the mouse recombining segment share DNA sequence homology

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

The human CK gene segment and the kappa deleting element are closely linked

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Ordered activation of the Ig lambda locus in Abelson B cell lines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Clonal silencing of self-reactive B lymphocytes in a transgenic mouse model

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Immunoglobulin lambda gene rearrangement can precede kappa gene rearrangement

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Murine lambda gene rearrangements: the stochastic model prevails over the ordered model

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Peripheral deletion of self-reactive B cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2351955

Contribution of Receptor Editing to the Antibody Repertoire

3 November 2018

1 reference

12 December 2020

Double producers of kappa and lambda define a subset of B cells in mouse plasmacytomas

1 reference

12 December 2020

Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human

1 reference

12 December 2020

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1 reference

12 December 2020

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

12 December 2020

A physical map and analysis of the murine C kappa-RS region show the presence of a conserved element

1 reference

12 December 2020

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

1 reference

12 December 2020

Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion

1 reference

12 December 2020

Transcription and recombination of the murine RS element

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12 December 2020

The role of Ig beta in precursor B cell transition and allelic exclusion

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12 December 2020

Editing disease-associated autoantibodies

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12 December 2020

Functional dissection of systemic lupus erythematosus using congenic mouse strains

1 reference

12 December 2020

Recombining sequence recombination in normal kappa-chain-expressing B cells

1 reference

12 December 2020

10.1016/J.IMMUNI.2007.12.011

Identifiers

DOI

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

18261939

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