Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin. (Q41911490)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447845%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin (English)

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5 March 2020

2

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Ian S Patten

4

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author name string

Mun Chun Chan

1

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5 March 2020

Srilatha Raghuram

3

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Caitlin Farrell

5

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Zolt Arany

6

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publication date

22 January 2014

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5 March 2020

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volume

4

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issue

1

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page(s)

2

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describes a project that uses

5 March 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice

5 June 2018

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Muscular dystrophy begins early in embryonic development deriving from stem cell loss and disrupted skeletal muscle formation

5 June 2018

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Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling.

5 June 2018

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PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

5 June 2018

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The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Expression of full-length utrophin prevents muscular dystrophy in mdx mice

5 June 2018

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5 June 2018

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Subtle neuromuscular defects in utrophin-deficient mice

5 June 2018

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5 June 2018

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X chromosome-linked muscular dystrophy (mdx) in the mouse

5 June 2018

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Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

5 June 2018

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Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3914847

Rescue of dystrophic skeletal muscle by PGC-1α involves restored expression of dystrophin-associated protein complex components and satellite cell signaling.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3914847

Resveratrol decreases inflammation and increases utrophin gene expression in the mdx mouse model of Duchenne muscular dystrophy

18 August 2018

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Quantitative proteomic analysis of dystrophic dog muscle.

18 August 2018

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Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats

18 August 2018

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High-throughput quantitative real-time PCR.

18 August 2018

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A role for the transcriptional coactivator PGC-1alpha in muscle refueling

18 August 2018

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A rapid, simple, and humane method for submandibular bleeding of mice using a lancet

18 August 2018

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Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.

18 August 2018

1 reference

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Effects of iron deprivation on the pathology and stress protein expression in murine X-linked muscular dystrophy

18 August 2018

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Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.

18 August 2018

1 reference

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Muscle fibers of mdx mice are more vulnerable to exercise than those of normal mice.

18 August 2018

1 reference

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Duchenne muscular dystrophy

18 August 2018

1 reference

12 December 2020

MyoD is required for myogenic stem cell function in adult skeletal muscle

1 reference

12 December 2020

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice

1 reference

12 December 2020

mdx mice show progressive weakness and muscle deterioration with age

1 reference

12 December 2020

An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation

1 reference

12 December 2020

Muscle cells from mdx mice have an increased susceptibility to oxidative stress

1 reference

12 December 2020

The formation of terminal fields in the absence of competitive interactions among primary motoneurons in the zebrafish

1 reference

12 December 2020

Histological parameters for the quantitative assessment of muscular dystrophy in the mdx-mouse

1 reference

12 December 2020

Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

1 reference

12 December 2020

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

1 reference

12 December 2020

Green tea extract decreases muscle necrosis in mdx mice and protects against reactive oxygen species

1 reference

12 December 2020

Peroxisome proliferator-activated receptor γ coactivator1- gene α transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscle

1 reference

12 December 2020

Identifiers

DOI

10.1186/2044-5040-4-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447845%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447845%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

24447845

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24447845%20AND%20SRC:MED&resulttype=core&format=json