Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol (Q41948967)

14 October 2017

Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol (English)

1 reference

14 October 2017

endoplasmic reticulum

0 references

author

Rodney E Infante

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Arun Radhakrishnan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Rodney Elwood Infante

1

1 reference

14 October 2017

Arun Radhakrishnan

2

1 reference

14 October 2017

language of work or name

English

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publication date

17 April 2017

1 reference

14 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

6 June 2020

cites work

1 reference

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5 June 2018

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5 June 2018

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Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

5 June 2018

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Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

5 June 2018

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5 June 2018

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Use of mutant 125I-perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

5 June 2018

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Fluorescence image screening for chemical compounds modifying cholesterol metabolism and distribution

5 June 2018

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A mouse macrophage lipidome

5 June 2018

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Accessibility of cholesterol in endoplasmic reticulum membranes and activation of SREBP-2 switch abruptly at a common cholesterol threshold

5 June 2018

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Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

5 June 2018

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Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes

5 June 2018

1 reference

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

5 June 2018

1 reference

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Cholesterol synthesis inhibitor U18666A and the role of sterol metabolism and trafficking in numerous pathophysiological processes

5 June 2018

1 reference

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Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis

5 June 2018

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Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding

5 June 2018

1 reference

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Intracellular sterol dynamics

5 June 2018

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Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

5 June 2018

1 reference

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Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance

5 June 2018

1 reference

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Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

5 June 2018

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Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

5 June 2018

1 reference

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Niemann-Pick C research from mouse to gene

5 June 2018

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How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids

5 June 2018

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Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

5 June 2018

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Primary familial xanthomatosis with involvement and calcification of the adrenals. Report of two more cases in siblings of a previously described infant.

5 June 2018

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Probing red cell membrane cholesterol movement with cyclodextrin

5 June 2018

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Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

5 June 2018

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Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

5 June 2018

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Identification of HE1 as the second gene of Niemann-Pick C disease

5 June 2018

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

5 June 2018

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

5 June 2018

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Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system

5 June 2018

1 reference

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Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

5 June 2018

1 reference

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Different rates of DNA synthesis during the S phase of log phase HeLa S3, WI-38, and 2RA cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Enzyme deficiency in cholesteryl ester storage idisease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

A receptor-mediated pathway for cholesterol homeostasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Plasma membranes contain half the phospholipid and 90% of the cholesterol and sphingomyelin in cultured human fibroblasts.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Regulation of the mevalonate pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Lipoproteins activate acyl-coenzyme A:cholesterol acyltransferase in macrophages only after cellular cholesterol pools are expanded to a critical threshold level

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Restoration of a regulatory response to low density lipoprotein in acid lipase-deficient human fibroblasts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease

5 June 2018

1 reference

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The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5433840

The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

18 August 2018

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Tissue fraction-past and present

18 August 2018

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Crossref

https://api.crossref.org/works/10.7554%2FELIFE.25466

Quantitation of the pool of cholesterol associated with acyl-CoA:cholesterol acyltransferase in human fibroblasts

21 January 2018

1 reference

12 December 2020

Evidence for a cholesterol transport pathway from lysosomes to endoplasmic reticulum that is independent of the plasma membrane

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12 December 2020

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

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12 December 2020

Tissue fractionation. Past and present

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12 December 2020

RNA synthesis in rat liver cells with different DNA contents

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12 December 2020

The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one

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12 December 2020

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

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12 December 2020

Intracellular trafficking of cholesterol monitored with a cyclodextrin

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12 December 2020

Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes

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12 December 2020

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

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12 December 2020

Identifiers

DOI

10.7554/ELIFE.25466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28414269%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

28414269

1 reference