Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL (Q24652984)

Journal of Lipid Research

Europe PubMed Central

title

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL (English)

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2

Joseph L Goldstein

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author name string

Michael S Brown

series ordinal

1

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language of work or name

English

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publication date

April 2009

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published in

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volume

50 Suppl

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issue

Supplement

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page(s)

S15-27

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cites work

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Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro

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Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis

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Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution

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Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

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SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

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Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

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Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

28 September 2017

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Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning

28 September 2017

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28 September 2017

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Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

28 September 2017

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42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter

28 September 2017

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Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

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Steroid Requirements for Suppression of HMG CoA Reductase Activity in Cultured Human Fibroblasts

28 September 2017

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Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance

28 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674699

Gene amplification and drug resistance in cultured murine cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674699

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

30 May 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Fatty acid auxotrophy in Drosophila larvae lacking SREBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

21 January 2018

Getting into the Golgi

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

Cholesterol biosynthesis in preparations of liver from normal, fasting, x-irradiated, cholesterol-fed, triton, or delta 4-cholesten-3-one-treated rats.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674699

Purification of the low density lipoprotein receptor, an acidic glycoprotein of 164,000 molecular weight

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674699

Evidence for coordinate expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase ad low density lipoprotein binding activity

28 November 2018

1 reference

12 December 2020

Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum

1 reference

12 December 2020

Regulation of Hepatic 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Synthesis

1 reference

12 December 2020

Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol

1 reference

12 December 2020

Lipid metabolism and atherosclerosis

1 reference

12 December 2020

Cholesterol synthesis by liver. III. Its regulation by ingested cholesterol

1 reference

12 December 2020

Cholesterol metabolism. I. Effect of dietary cholesterol on the synthesis of cholesterol in dog tissue in vitro

1 reference

12 December 2020

The effect of some dietary additions on the synthesis of cholesterol from acetate in vitro

1 reference

12 December 2020

Suppression of hepatic cholesterol synthesis in the rat by cholesterol feeding

1 reference

12 December 2020

METCALF AND BELL UPON SALPIDAe

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R800054-JLR200

7 January 2021