Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa (Q41967871)

14 October 2017

Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa (English)

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14 October 2017

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Claudio Punzo

1

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14 October 2017

Karl Kornacker

series ordinal

2

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14 October 2017

Constance L Cepko

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3

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14 October 2017

language of work or name

English

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publication date

7 December 2008

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14 October 2017

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14 October 2017

12

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14 October 2017

1

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14 October 2017

44-52

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https://scigraph.springernature.com/pub.10.1038/nn.2234

14 October 2017

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cites work

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Antioxidants reduce cone cell death in a model of retinitis pigmentosa

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Identification and characterization of rod-derived cone viability factor

5 June 2018

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5 June 2018

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Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

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Regulation of lamp2a levels in the lysosomal membrane

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Loss of cone molecular markers in rhodopsin-mutant human retinas with retinitis pigmentosa

5 June 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

5 June 2018

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Selective transplantation of rods delays cone loss in a retinitis pigmentosa model

5 June 2018

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

5 June 2018

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Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3.

5 June 2018

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Morphological, physiological, and biochemical changes in rhodopsin knockout mice

5 June 2018

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Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse

5 June 2018

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Photoreceptor transplants increase host cone survival in the retinal degeneration (rd) mouse

5 June 2018

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Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase

5 June 2018

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Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene

5 June 2018

1 reference

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Survival factors in retinal degenerations

5 June 2018

1 reference

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

5 June 2018

1 reference

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Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

5 June 2018

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Visual acuity loss in retinitis pigmentosa. Relationship to visual field loss

5 June 2018

1 reference

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Mouse opsin. Gene structure and molecular basis of multiple transcripts.

5 June 2018

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Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

5 June 2018

1 reference

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A locus control region adjacent to the human red and green visual pigment genes

5 June 2018

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Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa.

5 June 2018

1 reference

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Ultrasound-guided in utero injections allow studies of the development and function of the eye.

18 August 2018

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A mutation in the cone-specific pde6 gene causes rapid cone photoreceptor degeneration in zebrafish.

18 August 2018

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Apoptosis and autophagy in photoreceptors exposed to oxidative stress.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

A diffusible factor from normal retinal cells promotes rod photoreceptor survival in an in vitro model of retinitis pigmentosa.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339764

Chaperone-Mediated Autophagy

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.2234

Lactate released by Müller glial cells is metabolized by photoreceptors from mammalian retina

21 January 2018

1 reference

12 December 2020

Monoclonal antibodies to rhodopsin: characterization, cross-reactivity, and application as structural probes

1 reference

12 December 2020

Trafficking of molecules and metabolic signals in the retina

1 reference

12 December 2020

Reporter gene expression in cones in transgenic mice carrying bovine rhodopsin promoter/lacZ transgenes

1 reference

12 December 2020

Expression of rhodopsin promoter transgene product in both rods and cones

1 reference

12 December 2020

Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa

1 reference

12 December 2020

Identifiers

DOI

10.1038/NN.2234

1 reference

Dimensions Publication ID

14 October 2017

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1 reference

14 October 2017

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