An invertebrate model to evaluate virulence in Aspergillus fumigatus: the role of azole resistance. (Q42004623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

An invertebrate model to evaluate virulence in Aspergillus fumigatus: the role of azole resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

main subject

Aspergillus fumigatus

0 references

author

William Hope

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Emilio Cendejas-Bueno

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Emilia Mellado

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Howard S

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

A Gomez-Lopez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

A Forastiero

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

L Gregson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

J L Livermore

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

M Cuenca-Estrella

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

publication date

4 February 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Medical Mycology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

311-319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577012%20AND%20SRC:MED&resulttype=core&format=json

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness

9 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

The contribution of animal models of aspergillosis to understanding pathogenesis, therapy and virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Vertebrate innate immunity resembles a mosaic of invertebrate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Worms and flies as genetically tractable animal models to study host-pathogen interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Galleria mellonella and the study of fungal pathogenesis: making the case for another genetically tractable model host

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Susceptibility of larvae of Galleria mellonella to infection by Aspergillus fumigatus is dependent upon stage of conidial germination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Use of Turbidimetric Growth Curves for Early Determination of Antifungal Drug Resistance of Filamentous Fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Pathogenicity of Aspergillus fumigatus mutants assessed in Galleria mellonella matches that in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

A family of human receptors structurally related to Drosophila Toll

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Presence of IL-1- and TNF-like molecules in Galleria mellonella (Lepidoptera) haemocytes and in an insect cell line Fromestigmene acraea (Lepidoptera).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Fungal virulence in a lepidopteran model is an emergent property with deterministic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Invertebrate immunity--a primer for the non-specialist

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022

Azole Antifungal Resistance Today: Focus on Aspergillus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMMY%2FMYT022