The Misregulation of Cell Adhesion Components during Tumorigenesis: Overview and Commentary (Q42009631)

15 October 2017

The Misregulation of Cell Adhesion Components during Tumorigenesis: Overview and Commentary (English)

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15 October 2017

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Claudia D Andl

1

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15 October 2017

30 September 2010

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15 October 2017

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15 October 2017

2010

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Creative Commons Attribution 3.0 Unported

15 October 2017

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Adherens and tight junctions: structure, function and connections to the actin cytoskeleton

5 June 2018

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Decreased plakophilin-1 expression promotes increased motility in head and neck squamous cell carcinoma cells

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.

5 June 2018

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5 June 2018

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p120-ctn: A nexus for contextual signaling via Rho GTPases

5 June 2018

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Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments

5 June 2018

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The canonical Wnt signalling pathway and its APC partner in colon cancer development

5 June 2018

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5 June 2018

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Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells

5 June 2018

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5 June 2018

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Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

5 June 2018

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5 June 2018

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Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn

5 June 2018

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Roles of nectins in cell adhesion, migration and polarization.

5 June 2018

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Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin

5 June 2018

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Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin

5 June 2018

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Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes

5 June 2018

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Biology and pathology of nectins and nectin-like molecules

5 June 2018

1 reference

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Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.

5 June 2018

1 reference

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Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

5 June 2018

1 reference

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Desmoplakin is required for microvascular tube formation in culture

5 June 2018

1 reference

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Cadherin switch in tumor progression

5 June 2018

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Epidermal growth factor suppresses induction by progestin of the adhesion protein desmoplakin in T47D breast cancer cells

5 June 2018

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Endothelial cell-cell junctions: happy together

5 June 2018

1 reference

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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

5 June 2018

1 reference

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Dual roles of E-cadherin in prostate cancer invasion

5 June 2018

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Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

5 June 2018

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Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses

5 June 2018

1 reference

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A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.

5 June 2018

1 reference

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Cell migration: Rho GTPases lead the way

5 June 2018

1 reference

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Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line

5 June 2018

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E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles

5 June 2018

1 reference

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FAK regulates biological processes important for the pathogenesis of cancer

5 June 2018

1 reference

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Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability

5 June 2018

1 reference

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Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin

5 June 2018

1 reference

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Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

5 June 2018

1 reference

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Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

5 June 2018

1 reference

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Focal adhesion kinase in cancer

5 June 2018

1 reference

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Focal adhesion kinase: the first ten years

5 June 2018

1 reference

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Direct cadherin-activated cell signaling: a view from the plasma membrane

5 June 2018

1 reference

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5 June 2018

1 reference

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N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Epithelial-mesenchymal transitions in tumour progression

5 June 2018

1 reference

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Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

5 June 2018

1 reference

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Desmoplakin is essential in epidermal sheet formation

5 June 2018

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The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin

5 June 2018

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The hepatitis B virus HBx protein induces adherens junction disruption in a src-dependent manner.

5 June 2018

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Cadherins in embryonic and neural morphogenesis

5 June 2018

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

5 June 2018

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Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation.

5 June 2018

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Control of beta-catenin signaling in tumor development.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Developmental defects in mouse embryos lacking N-cadherin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Cadherin binding sites of plakoglobin: localization, specificity and role in targeting to adhering junctions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Embryonic heart and skin defects in mice lacking plakoglobin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasive phenotype of human papilloma virus-transfected keratinocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: identification of unique and shared domains.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Lack of beta-catenin affects mouse development at gastrulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

E-cadherin null mutant embryos fail to form a trophectoderm epithelium

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Autoantibodies against adhesion molecules and structures in blistering skin diseases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Plakoglobin: a protein common to different kinds of intercellular adhering junctions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Extrajunctional distribution of N-cadherin in cultured human endothelial cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

The molecular composition and function of desmosomes.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Hypermethylation of epithelial-cadherin gene promoter is associated with Epstein-Barr virus in nasopharyngeal carcinoma.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Nasal inverted papilloma expresses the muscle segment homeobox gene Msx2: possible prognostic implications.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Loss of cell adhesion in Dsg3bal-Pas mice with homozygous deletion mutation (2079del14) in the desmoglein 3 gene.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952821

Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2010%2F174715

The area composita of adhering junctions connecting heart muscle cells of vertebrates. VII. The different types of lateral junctions between the special cardiomyocytes of the conduction system of ovine and bovine hearts

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2010%2F174715

A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated

21 January 2018

1 reference

12 December 2020

Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer

1 reference

12 December 2020

Expression of claudin-3 and claudin-4 in normal, hyperplastic, and malignant endometrial tissue

1 reference

12 December 2020

Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals

1 reference

12 December 2020

Possible involvement of adherens junction plaque proteins in tumorigenesis and metastasis

1 reference

12 December 2020

Megaintestine in claudin-15-deficient mice

1 reference

12 December 2020

Loss of desmoglein 1 expression associated with worse prognosis in head and neck squamous cell carcinoma patients

1 reference

12 December 2020

Alterations of the cadherin-catenin cell adhesion system in cancers

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/174715

1 reference

15 October 2017

1 reference

15 October 2017

1 reference

PMCID

2952821