Effect of protein binding on the pharmacological activity of highly bound antibiotics (Q42015540)

15 October 2017

Effect of protein binding on the pharmacological activity of highly bound antibiotics (English)

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15 October 2017

1 reference

7

Hartmut Derendorf

1 reference

15 October 2017

Stephan Schmidt

1

1 reference

15 October 2017

Katharina Röck

2

1 reference

15 October 2017

Martina Sahre

3

1 reference

15 October 2017

Olaf Burkhardt

4

1 reference

15 October 2017

Martin Brunner

5

1 reference

15 October 2017

Maximilian T Lobmeyer

6

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15 October 2017

language of work or name

English

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publication date

8 September 2008

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Antimicrobial Agents and Chemotherapy

15 October 2017

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15 October 2017

52

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15 October 2017

11

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15 October 2017

3994-4000

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Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Pharmacokinetic/pharmacodynamic evaluation of anti-infective agents

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effect of ertapenem protein binding on killing of bacteria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Bacterial persistence as a phenotypic switch

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Clinical use of ceftriaxone: a pharmacokinetic-pharmacodynamic perspective on the impact of minimum inhibitory concentration and serum protein binding

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Free drug concentration monitoring in clinical practice. Rationale and current status

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Plasma protein binding of ceftriaxone.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Doxycycline binding to plasma albumin of several species

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Clinical pharmacokinetics of ceftriaxone

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Enhancing effect of serum ultrafiltrate on the activity of cephalosporins against gram-negative bacilli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effects of supraphysiologic temperature and broth dilution on serum protein binding

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Microdialysis sampling for determination of plasma protein binding of drugs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effect of protein binding of daptomycin on MIC and antibacterial activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Plasma protein binding of fluoroquinolones affects antimicrobial activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effect of human plasma on the antimicrobial activity of iclaprim in vitro

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effects of human albumin and serum on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumoniae.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Determination of the extent of protein binding of antibiotics by means of an automated continuous ultrafiltration method

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Determination of free ertapenem in plasma and bronchoalveolar lavage by high-performance liquid chromatography with ultraviolet detection

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Impact of plasma protein binding on antimicrobial activity using time-killing curves

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Binding study of drug with bovine serum album using a combined technique of microdialysis with flow-injection chemiluminescent detection

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Influence of protein binding under controlled conditions on the bactericidal activity of daptomycin in an in vitro pharmacodynamic model

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effect of protein binding on the in vitro activity and pharmacodynamics of faropenem

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Interaction of ceftriaxone with penicillin-binding proteins of Escherichia coli in the presence of human serum albumin

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Comparison of plasma and free tissue levels of ceftriaxone in rats by microdialysis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Effects of concentration-dependent plasma protein binding on ceftriaxone kinetics.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

Equilibrium dialysis, ultrafiltration, and ultracentrifugation compared for determining the plasma-protein-binding characteristics of valproic acid.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573140

In vitro effect of the presence of human albumin or human serum on the bactericidal activity of daptomycin against strains with the main resistance phenotypes in Gram-positives

17 August 2018

1 reference

12 December 2020

Effect of Free Fatty Acids on Protein Binding of Antimicrobial Agents

1 reference

12 December 2020

Study of the influence of protein binding on serum bactericidal titres and killing rates in volunteers receiving ceftazidime, cefotaxime and ceftriaxone

1 reference

12 December 2020

Anomalous effect of serum on the antimicrobial activity of cefoperazone

1 reference

12 December 2020

Effect of protein binding on antibiotic activity in vivo

1 reference

12 December 2020

Drug-protein interaction: the binding of cephalosporins to albumins

1 reference

12 December 2020

Influence of protein binding on the pharmacodynamics of ceftazidime or ceftriaxone against gram-positive and gram-negative bacteria in an in vitro infection model

1 reference

12 December 2020

Pharmacokinetic/pharmacodynamic modeling of in vitro activity of azithromycin against four different bacterial strains

1 reference

12 December 2020

Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis

1 reference

12 December 2020

Integration of pharmacokinetic/pharmacodynamic modeling and simulation in the development of new anti-infective agents - minimum inhibitory concentration versus time-kill curves

1 reference

12 December 2020

Pharmacokinetics of Rocephin, a highly active new cephalosporin with an exceptionally long biological half-life

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00427-08

1 reference

15 October 2017

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15 October 2017

PubMed publication ID

18779351

1 reference