Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity (Q42031529)

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scientific article published on June 2006

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English	Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity	scientific article published on June 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

crystal structure

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Miroslaw K Gorny

object named as

Miroslaw K Gorny

2

0 references

Ian Andrew Wilson

4

object named as

Ian A Wilson

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

author name string

Robyn L Stanfield

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Susan Zolla-Pazner

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

0 references

publication date

1 June 2006

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

80

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

12

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

6093-6105

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Raster3D: photorealistic molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Structure of a V3-containing HIV-1 gp120 core

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Conformational properties of HIV-1 gp120/V3 immunogenic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Structure of an unliganded simian immunodeficiency virus gp120 core

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade a and clade B v3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Solid-state NMR yields structural constraints on the V3 loop from HIV-1 Gp120 bound to the 447-52D antibody Fv fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

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5 June 2018

Effect of soluble CD4 on exposure of epitopes on primary, intact, native human immunodeficiency virus type 1 virions of different genetic clades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Conformational model for the consensus V3 loop of the envelope protein gp120 of HIV-1 in a 20% trifluoroethanol/water solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Recognition properties of V3-specific antibodies to V3 loop peptides derived from HIV-1 gp120 presented in multiple conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

1 reference

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5 June 2018

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

HIV-1 envelope determinants for cell tropism and chemokine receptor use.

1 reference

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5 June 2018

Immunotyping of human immunodeficiency virus type 1 (HIV): an approach to immunologic classification of HIV

1 reference

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5 June 2018

Further additions to MolScript version 1.4, including reading and contouring of electron-density maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Standard conformations for the canonical structures of immunoglobulins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Glycosylation affects both the three-dimensional structure and antibody binding properties of the HIV-1IIIB GP120 peptide RP135.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

NMR structure of the principal neutralizing determinant of HIV-1 displayed in filamentous bacteriophage coat protein.

1 reference

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5 June 2018

Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site

1 reference

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5 June 2018

Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies

1 reference

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5 June 2018

Structure and polymorphism of HIV-1 third variable loops

1 reference

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5 June 2018

Conformational features of a synthetic cyclic peptide corresponding to the complete V3 loop of the RF HIV-1 strain in water and water/trifluoroethanol solutions.

1 reference

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5 June 2018

The molecular surface package

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5 June 2018

Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

5 June 2018

Shape complementarity at protein/protein interfaces

1 reference

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5 June 2018

Satisfying hydrogen bonding potential in proteins

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5 June 2018

Human immunodeficiency virus (HIV) antigens: structure and serology of multivalent human mucin MUC1-HIV V3 chimeric proteins

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5 June 2018

The complete Consensus V3 loop peptide of the envelope protein gp120 of HIV-1 shows pronounced helical character in solution

1 reference

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5 June 2018

Crystal structure of the principal neutralization site of HIV-1

1 reference

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5 June 2018

NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of envelope protein gp120 from the RF strain of human immunodeficiency virus

1 reference

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5 June 2018

Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains

1 reference

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5 June 2018

Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution

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5 June 2018

Complete nucleotide sequences of functional clones of the AIDS virus

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5 June 2018

Three-dimensional structure of an antibody-antigen complex

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5 June 2018

Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120.

1 reference

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5 June 2018

Solution conformation of a peptide corresponding to the principal neutralizing determinant of HIV-1IIIB: a two-dimensional NMR study

1 reference

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5 June 2018

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

1 reference

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5 June 2018

Side-chain torsional potentials: effect of dipeptide, protein, and solvent environment

1 reference

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5 June 2018

Antibody elbow angles are influenced by their light chain class

1 reference

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17 August 2018

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

1 reference

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17 August 2018

Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

17 August 2018

V3-specific polyclonal antibodies affinity purified from sera of infected humans effectively neutralize primary isolates of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472588

17 August 2018

A structure-based approach to a synthetic vaccine for HIV-1.

1 reference

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17 August 2018

Secondary structural elements as a basis for antibody recognition in the immunodominant region of human immunodeficiency viruses 1 and 2.

1 reference

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17 August 2018

Conformational preferences of a chimeric peptide HIV-1 immunogen from the C4-V3 domains of gp120 envelope protein of HIV-1 CAN0A based on solution NMR: comparison to a related immunogenic peptide from HIV-1 RF.

1 reference

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17 August 2018

Structural studies on synthetic peptides from the principal neutralizing domain of HIV-1 gp120 that bind to CD4 and enhance HIV-1 infection

1 reference

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17 August 2018

NMR study of the peptide present in the principal neutralizing determinant (PND) of HIV-1 envelope glycoprotein gp120

1 reference

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12 December 2020

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Synthesis, characterization and conformational analysis of gp 120-derived synthetic peptides that specifically enhance HIV-1 infectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural comparison of a 15 residue peptide from the V3 loop of HIV-1IIIb and an O-glycosylated analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-dimensional NMR spectroscopy of peptides on beads

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of the V3 loop of a Thailand HIV isolate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic V3-loop-related HIV-1 conjugate vaccines. Synthesis, conformation and immunological properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cross-clade neutralizing activity of a human monoclonal antibody is determined by the GPGR V3 motif of HIV type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The binding of a glycoprotein 120 V3 loop peptide to HIV-1 neutralizing antibodies. Structural implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural classification of CDR-H3 in antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local and global structural properties of the HIV-MN V3 loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic rings act as hydrogen bond acceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16731948

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00205-06

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

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