A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile. (Q42111372)

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English	A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.	scientific article

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27089538%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile (English)

1 reference

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2 April 2020

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click chemistry

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based on heuristic

inferred from title

corrigendum / erratum

Corrigendum: A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.

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Giancarlo Biagini

5

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2 April 2020

Hanafy M Ismail

1

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2 April 2020

Sitthivut Charoensutthivarakul

4

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2 April 2020

6

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2 April 2020

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Victoria E Barton

2

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2 April 2020

Matthew Panchana

3

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2 April 2020

Paul M O'Neill

7

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2 April 2020

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18 April 2016

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2 April 2020

Angewandte Chemie International Edition

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2 April 2020

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2 April 2020

22

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2 April 2020

6401-6405

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2 April 2020

Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.

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29 May 2018

Monoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel).

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29 May 2018

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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29 May 2018

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

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29 May 2018

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

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29 May 2018

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

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29 May 2018

Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate

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29 May 2018

Artemisinin rewires the protein interaction network in cancer cells: network analysis, pathway identification, and target prediction

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29 May 2018

Protein S-glutathionylation in malaria parasites

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29 May 2018

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

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29 May 2018

Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.

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29 May 2018

The molecular mechanism of action of artemisinin--the debate continues.

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29 May 2018

Copper-free click chemistry for dynamic in vivo imaging

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29 May 2018

Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs.

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29 May 2018

Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein

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29 May 2018

Identification of an antimalarial synthetic trioxolane drug development candidate

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29 May 2018

Profiling enzyme activities in vivo using click chemistry methods

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29 May 2018

Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

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29 May 2018

Reaction of antimalarial endoperoxides with specific parasite proteins

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29 May 2018

Malaria: to kill a parasite

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17 August 2018

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action

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21 January 2018

Mechanisms and energetics of free radical initiated disulfide bond cleavage in model peptides and insulin by mass spectrometry.

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Further evidence supporting the importance of and the restrictions on a carbon-centered radical for high antimalarial activity of 1,2,4-trioxanes like artemisinin

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12 December 2020

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10.1002/ANIE.201512062

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2 April 2020

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2 April 2020

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