Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges. (Q42124925)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22655211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges (English)

1 reference

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3 February 2020

1 reference

Seyyed Mohammad Reza Kazemi-Bajestani

1

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3 February 2020

Vaibhav B. Patel

2

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3 February 2020

author name string

Wang Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22655211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Gavin Y Oudit

4

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3 February 2020

publication date

13 May 2012

1 reference

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Cardiology Research and Practice

3 February 2020

published in

1 reference

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3 February 2020

volume

2012

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3 February 2020

page(s)

823193

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Creative Commons Attribution 3.0 Unported

3 February 2020

copyright license

start time

1 January 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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17 August 2018

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Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.

17 August 2018

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Acute cardiovascular effects of apelin in humans: potential role in patients with chronic heart failure.

17 August 2018

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17 August 2018

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Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice

17 August 2018

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Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia

17 August 2018

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Effect of sinus rhythm restoration after electrical cardioversion on apelin and brain natriuretic Peptide prohormone levels in patients with persistent atrial fibrillation

17 August 2018

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Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction

17 August 2018

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Increased apelin following bone marrow mononuclear cell transplantation contributes to the improvement of cardiac function in patients with severe heart failure

17 August 2018

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Apelin protects heart against ischemia/reperfusion injury in rat.

17 August 2018

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Plasma apelin concentration is depressed following acute myocardial infarction in man.

17 August 2018

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Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Loss of angiotensin-converting enzyme 2 leads to impaired glucose homeostasis in mice.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Vascular effects of apelin in vivo in man.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Low plasma apelin levels in newly diagnosed type 2 diabetes mellitus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Apelin decreases the SR Ca2+ content but enhances the amplitude of [Ca2+]i transient and contractions during twitches in isolated rat cardiac myocytes.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Temporal changes in myocardial salvage kinases during reperfusion following ischemia: studies involving the cardioprotective adipocytokine apelin

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359660

The role of ACE2 in pulmonary diseases--relevance for the nephrologist

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F823193

Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F823193

Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely

21 January 2018

1 reference

12 December 2020

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

1 reference

12 December 2020

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

1 reference

12 December 2020

The value of apelin-36 and brain natriuretic peptide measurements in patients with first ST-elevation myocardial infarction

1 reference

12 December 2020

Downregulation of angiotensin converting enzyme II is associated with pacing-induced sustained atrial fibrillation

1 reference

12 December 2020

The epidemiology of heart failure

1 reference

12 December 2020

Reduced apelin levels in lone atrial fibrillation

1 reference

12 December 2020

Apelin: a potential link between inflammation and cardiovascular disease in end stage renal disease patients

1 reference

12 December 2020

Apelin Plasma Levels Predict Arrhythmia Recurrence in Patients with Persistent Atrial Fibrillation

1 reference

12 December 2020

Direct effects of apelin on cardiomyocyte contractility and electrophysiology

1 reference

12 December 2020

Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure

1 reference

12 December 2020

Apelin: a novel marker for the patients with first ST-elevation myocardial infarction

1 reference

12 December 2020

Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice

1 reference

12 December 2020

ACE2 overexpression ameliorates left ventricular remodeling and dysfunction in a rat model of myocardial infarction

1 reference

12 December 2020

Serum levels of apelin and ghrelin in patients with acute coronary syndromes and established coronary artery disease--KOZANI STUDY

1 reference

12 December 2020

Apelin Serum Levels are not Associated with Early Atherosclerosis or Fat Distribution in Young Subjects with Increased Risk for Type 2 Diabetes

1 reference

12 December 2020

Reduced circulating apelin in essential hypertension and its association with cardiac dysfunction

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/823193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22655211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22655211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

22655211

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22655211%20AND%20SRC:MED&resulttype=core&format=json