The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats (Q42126431)

16 October 2017

The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats (English)

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16 October 2017

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Natalia A Muraleva

1

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16 October 2017

Oyuna S Kozhevnikova

2

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16 October 2017

Anna A Zhdankina

3

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16 October 2017

Natalia A Stefanova

4

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16 October 2017

Tatyana V Karamysheva

5

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16 October 2017

Anzhella Z Fursova

6

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16 October 2017

Nataliya G Kolosova

7

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16 October 2017

1 January 2014

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16 October 2017

7

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inferred from page(s)

published in

Cell Cycle

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16 October 2017

13

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16 October 2017

22

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16 October 2017

3499-3505

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describes a project that uses

16 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4614531/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Senescence-accelerated OXYS rats: a model of age-related cognitive decline with relevance to abnormalities in Alzheimer disease

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Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure.

29 May 2018

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ER stress-induced cell death mechanisms

29 May 2018

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Rapamycin suppresses brain aging in senescence-accelerated OXYS rats

29 May 2018

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Rat retinal transcriptome: effects of aging and AMD-like retinopathy

29 May 2018

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Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD.

29 May 2018

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Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster

29 May 2018

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The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats.

29 May 2018

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Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction

29 May 2018

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Novel roles for α-crystallins in retinal function and disease

29 May 2018

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Secretion of αB-Crystallin via exosomes: New clues to the function of human retinal pigment epithelium

29 May 2018

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Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats.

29 May 2018

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SkQ1 treatment and food restriction--two ways to retard an aging program of organisms

29 May 2018

1 reference

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Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents.

29 May 2018

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Mitochondrial dysfunction in retinal diseases

29 May 2018

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Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression

29 May 2018

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29 May 2018

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Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

29 May 2018

1 reference

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New focus on alpha-crystallins in retinal neurodegenerative diseases

29 May 2018

1 reference

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αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide

29 May 2018

1 reference

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Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats.

29 May 2018

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alphaB-crystallin regulation of angiogenesis by modulation of VEGF.

29 May 2018

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An attempt to prevent senescence: a mitochondrial approach.

29 May 2018

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Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

29 May 2018

1 reference

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alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

29 May 2018

1 reference

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Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration

29 May 2018

1 reference

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The role of oxidative stress in the pathogenesis of age-related macular degeneration.

29 May 2018

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29 May 2018

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Association of AMD-like retinopathy development with an Alzheimer's disease metabolic pathway in OXYS rats.

29 May 2018

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Heat shock response and ionstasis: axis against neurodegeneration

17 August 2018

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SkQ1 slows development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats.

17 August 2018

1 reference

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Effect of vascular endothelial growth factor upregulation on retinal gene expression in the Kimba mouse.

17 August 2018

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Lipofuscin granule dynamics during development of age-related macular degeneration

17 August 2018

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Clinical and morphological characteristics of chorioretinal degeneration in early aging OXYS rats.

17 August 2018

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Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals.

17 August 2018

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Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells

17 August 2018

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Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614531

Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614531

Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25483086

12 December 2020

inferred from PubMed ID database lookup

[Potential of melatonin for prevention of age-related macular degeneration: experimental study]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25483086

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/15384101.2014.958393

1 reference

16 October 2017

1 reference

16 October 2017

1 reference