Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity (Q42129626)

17 October 2017

Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity (English)

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17 October 2017

5

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17 October 2017

12

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17 October 2017

Marc M Nowaczyk

8

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Karin Loser

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17 October 2017

Jenny Calow

1

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17 October 2017

Anna-Janina Behrens

2

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17 October 2017

Sonja Mader

3

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17 October 2017

Ulrike Bockau

4

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17 October 2017

David J Harvey

6

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17 October 2017

Kai U Cormann

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17 October 2017

Karin Loser

9

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17 October 2017

Daniel Schinor

10

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17 October 2017

Marcus W W Hartmann

11

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17 October 2017

3 September 2016

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17 October 2017

Monoclonal Antibodies

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17 October 2017

8

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17 October 2017

8

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17 October 2017

1498-1511

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Creative Commons Attribution-NonCommercial 3.0 Unported

17 October 2017

start time

3 September 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor

29 May 2018

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Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.

29 May 2018

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Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study.

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High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans

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Expression, secretion and surface display of a human alkaline phosphatase by the ciliate Tetrahymena thermophila

29 May 2018

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Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC

29 May 2018

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Optimal and consistent protein glycosylation in mammalian cell culture

29 May 2018

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Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions

29 May 2018

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Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry

29 May 2018

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A recombinase system facilitates cloning of expression cassettes in the ciliate Tetrahymena thermophila

29 May 2018

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Endoplasmic reticulum retention signal-dependent glycylation of the Hsp70/Grp170-related Pgp1p in Tetrahymena

29 May 2018

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Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

29 May 2018

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Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote

29 May 2018

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The bifunctional dihydrofolate reductase thymidylate synthase of Tetrahymena thermophila provides a tool for molecular and biotechnology applications

29 May 2018

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Secretion of functional human enzymes by Tetrahymena thermophila

29 May 2018

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High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G.

29 May 2018

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29 May 2018

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Applications of a travelling wave-based radio-frequency-only stacked ring ion guide

29 May 2018

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Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity

29 May 2018

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Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance

29 May 2018

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Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

29 May 2018

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The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms.

29 May 2018

1 reference

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Cloning and characterization of the gene encoding the highly expressed ribosomal protein l3 of the ciliated protozoan Tetrahymena thermophila. Evidence for differential codon usage in highly expressed genes

29 May 2018

1 reference

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Transient and stable DNA transformation of Tetrahymena thermophila by electroporation

29 May 2018

1 reference

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Analysis of genomic G + C content, codon usage, initiator codon context and translation termination sites in Tetrahymena thermophila

29 May 2018

1 reference

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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

29 May 2018

1 reference

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The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding.

29 May 2018

1 reference

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Germline and somatic transformation of mating Tetrahymena thermophila by particle bombardment

29 May 2018

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Glycosylation: heterogeneity and the 3D structure of proteins

29 May 2018

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29 May 2018

1 reference

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The Golgi apparatus of Tetrahymena thermophila

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Tetrahymena: a model for growth, cell cycle and nutritional studies, with biotechnological potential

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Secretion heterogeneity of lysosomal enzymes in Tetrahymena pyriformis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Efficient mass transformation of Tetrahymena thermophila by electroporation of conjugants

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Lysosomal hydrolase secretion byTetrahymena: A comparison of several intralysosomal enzymes with the isoenzymes released into the medium

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Effect of high mannose glycan pairing on IgG antibody clearance.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Separation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Development of a single column method for the separation of lipid- and protein-derived oligosaccharides

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Applications of CE SDS gel in development of biopharmaceutical antibody-based products

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

C-terminal lysine variants in fully human monoclonal antibodies: investigation of test methods and possible causes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

17 August 2018

Tetrahymena thermophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Fragmentation of negative ions from carbohydrates: part 2. Fragmentation of high-mannose N-linked glycans

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5098438

Antibodies to watch in 2015

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2016.1228504

A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2016.1228504

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

21 January 2018

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12 December 2020

Isolation and characterization of IgG1 with asymmetrical Fc glycosylation

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12 December 2020

The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism

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12 December 2020

Carbohydrates of lysosomal enzymes secreted by Tetrahymena pyriformis

1 reference

12 December 2020

New downstream processing strategy for the purification of monoclonal antibodies from transgenic tobacco plants

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12 December 2020

10.1080/19420862.2016.1228504

Identifiers

DOI

1 reference

release_67mi63ijwzdrja4hiys5oydtya

17 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/67mi63ijwzdrja4hiys5oydtya

24 November 2022

mapped directly with Wikidata item

1 reference

17 October 2017

PubMed publication ID

27594301

1 reference