An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells (Q42139586)

17 October 2017

An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells (English)

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17 October 2017

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Weiguo Cui

1

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17 October 2017

Ying Liu

2

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17 October 2017

Jason S Weinstein

3

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17 October 2017

Joseph Craft

4

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17 October 2017

Susan M Kaech

5

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17 October 2017

language of work or name

English

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publication date

1 November 2011

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17 October 2017

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17 October 2017

35

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17 October 2017

5

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17 October 2017

792-805

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describes a project that uses

17 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3431922/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Intrinsic IL-21 signaling is critical for CD8 T cell survival and memory formation in response to vaccinia viral infection

29 May 2018

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The transcription factor STAT3 is required for T helper 2 cell development

29 May 2018

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Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses

29 May 2018

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From vaccines to memory and back

29 May 2018

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Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.

29 May 2018

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IL-21 Deficiency Influences CD8 T Cell Quality and Recall Responses following an Acute Viral Infection

29 May 2018

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Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1

29 May 2018

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STAT5 is critical to maintain effector CD8+ T cell responses.

29 May 2018

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Generation of effector CD8+ T cells and their conversion to memory T cells

29 May 2018

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IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection

29 May 2018

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Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

29 May 2018

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29 May 2018

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CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

29 May 2018

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Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses

29 May 2018

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Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

29 May 2018

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Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory

29 May 2018

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mTOR regulates memory CD8 T-cell differentiation

29 May 2018

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Enhancing CD8 T-cell memory by modulating fatty acid metabolism

29 May 2018

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Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation

29 May 2018

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Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

29 May 2018

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Activation-dependent induction of Blimp-1.

29 May 2018

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The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer

29 May 2018

1 reference

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STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation.

29 May 2018

1 reference

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Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

29 May 2018

1 reference

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Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

29 May 2018

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Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

29 May 2018

1 reference

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

29 May 2018

1 reference

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Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

29 May 2018

1 reference

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Interleukin-10 plays an early role in generating virus-specific T cell anergy

29 May 2018

1 reference

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SOCS proteins, cytokine signalling and immune regulation

29 May 2018

1 reference

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

29 May 2018

1 reference

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Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

29 May 2018

1 reference

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Regulation of JAK-STAT signalling in the immune system

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Modelling T-cell memory by genetic marking of memory T cells in vivo

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Pathogen-specific CD8 T cell responses are directly inhibited by IL-10.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

IL-10 is required for optimal CD8 T cell memory following Listeria monocytogenes infection.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Serine protease inhibitor 2A is a protective factor for memory T cell development

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

CD8+ T cell contraction is controlled by early inflammation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Molecular and functional profiling of memory CD8 T cell differentiation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431922

Chemokine-guided CD4+ T cell help enhances generation of IL-6RalphahighIL-7Ralpha high prememory CD8+ T cells

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22118527

12 December 2020

inferred from PubMed ID database lookup

Bcl6 is essential for the generation of long-term memory CD4+ T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22118527

12 December 2020

inferred from PubMed ID database lookup

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22118527

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.IMMUNI.2011.09.017

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

22118527

1 reference