Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. (Q42144221)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19727141%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints (English)

1 reference

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6 February 2020

8

1 reference

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6 February 2020

James Wilson

10

1 reference

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6 February 2020

author name string

L H Vandenberghe

1

1 reference

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6 February 2020

E Breous

2

1 reference

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6 February 2020

H-J Nam

3

1 reference

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6 February 2020

G Gao

4

1 reference

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6 February 2020

R Xiao

5

1 reference

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6 February 2020

A Sandhu

6

1 reference

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6 February 2020

J Johnston

7

1 reference

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6 February 2020

M Agbandje-McKenna

9

1 reference

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6 February 2020

language of work or name

1 reference

1 December 2009

1 reference

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6 February 2020

1 reference

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6 February 2020

volume

16

1 reference

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6 February 2020

issue

12

1 reference

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6 February 2020

page(s)

1416-1428

1 reference

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https://scigraph.springernature.com/pub.10.1038/gt.2009.101

6 February 2020

exact match

0 references

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Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

29 May 2018

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29 May 2018

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Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus

29 May 2018

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Single amino acid changes can influence titer, heparin binding, and tissue tropism in different adeno-associated virus serotypes

29 May 2018

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29 May 2018

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High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes

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29 May 2018

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29 May 2018

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Novel caprine adeno-associated virus (AAV) capsid (AAV-Go.1) is closely related to the primate AAV-5 and has unique tropism and neutralization properties

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain

17 August 2018

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Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice.

17 August 2018

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Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid

17 August 2018

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High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses

17 August 2018

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Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

17 August 2018

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Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy

17 August 2018

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17 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FGT.2009.101

21 January 2018

Identifiers

DOI

10.1038/GT.2009.101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19727141%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19727141%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference