New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities. (Q42173095)

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scientific article published on March 2015

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English	New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities.	scientific article published on March 2015

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29 February 2020

New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities (English)

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Dominique Schols

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Christopher Cawthorne

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Steve Archibald

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Franck Denat

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Frédéric Boschetti

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Frédéric Boschetti

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Christine Goze

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Pauline Désogère

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Pauline Désogère

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Sophie Poty

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Helmut R Maëcke

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1 March 2015

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Dalton Transactions

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5004-5016

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29 February 2020

CXCR4 chemokine receptor overview: biology, pathology and applications in imaging and therapy

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Imaging agents for the chemokine receptor 4 (CXCR4).

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

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Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

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Cyclam complexes and their applications in medicine

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Quantitative structural activity relationship study of bis-tetraazacyclic compounds. A novel series of HIV-1 and HIV-2 inhibitors

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AMD3100 is a CXCR7 ligand with allosteric agonist properties

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Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection.

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A phase II study of plerixafor (AMD3100) plus G-CSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma

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64Cu-AMD3100--a novel imaging agent for targeting chemokine receptor CXCR4.

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Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography

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Synthesis and Evaluation of [(67)Ga]-AMD3100: A Novel Imaging Agent for Targeting the Chemokine Receptor CXCR4.

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21 January 2018

[⁹⁹mTc]O₂-AMD3100 as a SPECT tracer for CXCR4 receptor imaging

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21 January 2018

Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding

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21 January 2018

Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor.

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Dinickel and dicopper complexes with N,N-linked bis(cyclam) ligands. An ideal system for the investigation of electrostatic effects on the redox behavior of pairs of metal ions

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Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor

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10.1039/C4DT02972K

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29 February 2020

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29 February 2020

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