Why pain gets worse: the mechanism of heat hyperalgesia. (Q42181746)

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21 December 2019

title

Why pain gets worse: the mechanism of heat hyperalgesia (English)

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21 December 2019

2

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21 December 2019

Xuming Zhang

series ordinal

1

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21 December 2019

author name string

Xuming Zhang

series ordinal

1

1 reference

18 October 2017

language of work or name

1 reference

1 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17074974%20AND%20SRC:MED&resulttype=core&format=json

The Journal of General Physiology

21 December 2019

published in

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21 December 2019

volume

128

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21 December 2019

issue

5

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21 December 2019

page(s)

491-493

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Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.

21 December 2019

cites work

1 reference

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26 October 2017

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NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.

26 October 2017

1 reference

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Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate.

26 October 2017

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Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).

26 October 2017

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Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors

26 October 2017

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Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues

26 October 2017

1 reference

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Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

26 October 2017

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Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

26 October 2017

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Neurotrophin signal transduction in the nervous system

26 October 2017

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Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

26 October 2017

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Impaired nociception and pain sensation in mice lacking the capsaicin receptor

26 October 2017

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

26 October 2017

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A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin

26 October 2017

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Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.

26 October 2017

1 reference

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p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

29 May 2018

1 reference

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Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor

29 May 2018

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A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

17 August 2018

1 reference

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cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation

17 August 2018

1 reference

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Nerve growth factor-induced hyperalgesia in the neonatal and adult rat

17 August 2018

1 reference

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Specific Involvement of PKC-ε in Sensitization of the Neuronal Response to Painful Heat

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1085%2FJGP.200609676

21 January 2018

Identifiers

DOI

10.1085/JGP.200609676

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17074974%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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21 December 2019

PubMed publication ID

17074974

1 reference