The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling. (Q42185220)

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20 February 2020

title

The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling (English)

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20 February 2020

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Membrane protein [SARS-Cov]

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Stephen Kwok-Wing Tsui

5

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20 February 2020

Kwok-Fai Lau

4

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20 February 2020

Chan, H.Y.E.

6

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20 February 2020

author name string

Ho Tsoi

1

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20 February 2020

Li Li

2

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20 February 2020

Zhefan S Chen

3

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20 February 2020

language of work or name

English

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publication date

1 December 2014

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20 February 2020

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20 February 2020

volume

464

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20 February 2020

issue

3

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20 February 2020

page(s)

439-447

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Phosphorylation of p38 MAPK and its downstream targets in SARS coronavirus-infected cells

20 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20131461

Importance of Akt signaling pathway for apoptosis in SARS-CoV-infected Vero E6 cells

21 January 2018

1 reference

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JNK and PI3k/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells.

21 January 2018

1 reference

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The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway

21 January 2018

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Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

21 January 2018

1 reference

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SARS coronavirus induces apoptosis in Vero E6 cells

21 January 2018

1 reference

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Apoptosis induced by the SARS-associated coronavirus in Vero cells is replication-dependent and involves caspase

21 January 2018

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The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

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AKT/PKB signaling: navigating downstream

21 January 2018

1 reference

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PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors

21 January 2018

1 reference

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PI3K/Akt and apoptosis: size matters

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Signaling and transcriptional control of Fas ligand gene expression.

21 January 2018

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Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

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JNK signaling in apoptosis

21 January 2018

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Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection

21 January 2018

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The Genome sequence of the SARS-associated coronavirus

21 January 2018

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Characterization of a novel coronavirus associated with severe acute respiratory syndrome

21 January 2018

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A novel coronavirus associated with severe acute respiratory syndrome

21 January 2018

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The SARS coronavirus nucleocapsid protein induces actin reorganization and apoptosis in COS-1 cells in the absence of growth factors

21 January 2018

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In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila.

21 January 2018

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Severe acute respiratory syndrome coronavirus 3C-like protease-induced apoptosis

21 January 2018

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Adenovirus-mediated expression of the C-terminal domain of SARS-CoV spike protein is sufficient to induce apoptosis in Vero E6 cells

21 January 2018

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The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function.

21 January 2018

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Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein

21 January 2018

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Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus

21 January 2018

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The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles

21 January 2018

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Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus

21 January 2018

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Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

21 January 2018

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CAG expansion induces nucleolar stress in polyglutamine diseases

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

21 January 2018

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A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia

21 January 2018

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Fas ligand-induced apoptosis

21 January 2018

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Roles of MAPKKK ASK1 in stress-induced cell death.

21 January 2018

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Accelerated induction of apoptosis in insect cells by baculovirus-expressed SARS-CoV membrane protein

21 January 2018

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Apoptosis and inactivation of the PI3-kinase pathway by tetrocarcin A in breast cancers

21 January 2018

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The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

21 January 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20131461

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271362%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference