FMNL2 drives actin-based protrusion and migration downstream of Cdc42. (Q42188467)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22608513%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

FMNL2 drives actin-based protrusion and migration downstream of Cdc42 (English)

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Klemens Rottner

14

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Frieda Kage

5

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1 February 2020

Jennifer Rohn

8

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1 February 2020

Cord Brakebusch

10

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Matthias Geyer

11

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Theresia Stradal

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1

Jennifer Block

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1 February 2020

author name string

Dennis Breitsprecher

2

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1 February 2020

Sonja Kühn

3

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1 February 2020

Moritz Winterhoff

4

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1 February 2020

Robert Geffers

6

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1 February 2020

Patrick Duwe

7

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1 February 2020

Jan Faix

13

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language of work or name

English

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publication date

17 May 2012

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1 February 2020

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1 February 2020

volume

22

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1 February 2020

page(s)

1005-1012

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1 February 2020

issue

11

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The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed ends

1 February 2020

cites work

1 reference

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Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype.

26 October 2017

1 reference

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26 October 2017

Life at the leading edge

1 reference

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FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma

26 October 2017

1 reference

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Molecular mechanism of Ena/VASP-mediated actin-filament elongation.

26 October 2017

1 reference

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VASP is a processive actin polymerase that requires monomeric actin for barbed end association

26 October 2017

1 reference

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Assembly of filopodia by the formin FRL2 (FMNL3)

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

A nucleator arms race: cellular control of actin assembly

26 October 2017

1 reference

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Fifteen formins for an actin filament: a molecular view on the regulation of human formins.

26 October 2017

1 reference

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Unleashing formins to remodel the actin and microtubule cytoskeletons

26 October 2017

1 reference

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Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Filopodia formation induced by active mDia2/Drf3.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Overexpression of FMNL2 is closely related to metastasis of colorectal cancer

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Arp2/3 complex interactions and actin network turnover in lamellipodia.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Trafficking and signaling by fatty-acylated and prenylated proteins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

26 October 2017

The making of filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

26 October 2017

1 reference

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PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

26 October 2017

1 reference

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The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells

26 October 2017

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

26 October 2017

1 reference

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Phospholipids regulate localization and activity of mDia1 formin

26 October 2017

1 reference

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Interaction of the N- and C-terminal autoregulatory domains of FRL2 does not inhibit FRL2 activity.

29 May 2018

1 reference

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The Rho family GTPase Rif induces filopodia through mDia2.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.

29 May 2018

1 reference

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Control of the assembly of ATP- and ADP-actin by formins and profilin.

17 August 2018

1 reference

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Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

VASP dynamics during lamellipodia protrusion

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3765947

10.1016/J.CUB.2012.03.064

1 December 2018

Identifiers

DOI

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1 February 2020

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1 February 2020

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