Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1. (Q42200194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204013%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1 (English)

1 reference

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19 January 2020

main subject

protein ubiquitination

1 reference

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1

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19 January 2020

author name string

Lixin Wan

series ordinal

2

1 reference

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19 January 2020

Wenyi Wei

series ordinal

3

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19 January 2020

publication date

1 October 2010

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19 January 2020

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19 January 2020

volume

1

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19 January 2020

issue

10

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19 January 2020

page(s)

881-885

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Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction

19 January 2020

cites work

1 reference

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Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors

26 October 2017

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Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase

26 October 2017

1 reference

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mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

26 October 2017

1 reference

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

26 October 2017

1 reference

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

26 October 2017

1 reference

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mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase

26 October 2017

1 reference

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26 October 2017

Expanding mTOR signaling

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Defining the role of mTOR in cancer

26 October 2017

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AKT/PKB signaling: navigating downstream

26 October 2017

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Stress and mTORture signaling

26 October 2017

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

26 October 2017

1 reference

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

26 October 2017

1 reference

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mTOR and cancer: insights into a complex relationship

26 October 2017

1 reference

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

26 October 2017

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TOR signaling in growth and metabolism

26 October 2017

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Sgk kinases and their role in epithelial transport

26 October 2017

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Akt-regulated pathways in prostate cancer

26 October 2017

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

26 October 2017

1 reference

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High frequency of mutations of the PIK3CA gene in human cancers

26 October 2017

1 reference

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The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

26 October 2017

1 reference

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374330

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374330

Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer

26 October 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21204013

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13238-010-0123-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204013%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21204013%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21204013

1 reference