A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation. (Q42238933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15615773%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation (English)

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6 January 2020

2

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6 January 2020

Kenneth Yamada

8

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6 January 2020

Martin J. Humphries

9

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6 January 2020

Mark A. Travis

3

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6 January 2020

Paul Mould

5

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6 January 2020

author name string

Katherine Clark

1

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6 January 2020

Janet A Askari

4

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6 January 2020

Susan E Craig

6

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6 January 2020

Peter Newham

7

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6 January 2020

language of work or name

English

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publication date

22 December 2004

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6 January 2020

published in

Journal of Cell Science

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6 January 2020

volume

118

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6 January 2020

issue

Pt 2

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6 January 2020

page(s)

291-300

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6 January 2020

1 reference

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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

26 October 2017

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Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble

26 October 2017

1 reference

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Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

26 October 2017

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Mapping functional residues onto integrin crystal structures.

26 October 2017

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Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

26 October 2017

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Integrins: bidirectional, allosteric signaling machines

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Fibronectin at a glance

1 reference

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Conformational regulation of integrin structure and function

26 October 2017

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Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

26 October 2017

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Taking cell-matrix adhesions to the third dimension

26 October 2017

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Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

26 October 2017

1 reference

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

26 October 2017

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Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state

26 October 2017

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Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

26 October 2017

1 reference

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Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis

26 October 2017

1 reference

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Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.

26 October 2017

1 reference

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Getting integrins into shape: recent insights into how integrin activity is regulated by conformational changes

26 October 2017

1 reference

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A Binding Interface on the I Domain of Lymphocyte Function-associated Antigen-1 (LFA-1) Required for Specific Interaction with Intercellular Adhesion Molecule 1 (ICAM-1)

26 October 2017

1 reference

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Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

26 October 2017

1 reference

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Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.

26 October 2017

1 reference

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Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization

26 October 2017

1 reference

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Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function

26 October 2017

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The use of engineered E1A genes to transactivate the hCMV-MIE promoter in permanent CHO cell lines

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A novel regulatory epitope defined by a murine monoclonal antibody to the platelet GPIIb-IIIa complex (alpha IIb beta 3 integrin).

26 October 2017

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

29 May 2018

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Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

29 May 2018

1 reference

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Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

29 May 2018

1 reference

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

17 August 2018

1 reference

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

17 August 2018

1 reference

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Generation of a minimal alpha5beta1 integrin-Fc fragment

17 August 2018

1 reference

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A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions

17 August 2018

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17 August 2018

1 reference

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Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

1 December 2018

1 reference

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12 December 2020

'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization

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C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

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Rapid methods for isolation of human plasma fibronectin

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Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex

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12 December 2020

Identifiers

DOI

10.1242/JCS.01623

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15615773%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15615773%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

15615773

1 reference