Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat. (Q42409338)

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10 February 2020

title

Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat (English)

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10 February 2020

1

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10 February 2020

Richard A Cohen

5

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10 February 2020

author name string

Xiuyun Hou

2

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10 February 2020

David Jourd'heuil

3

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10 February 2020

Robert M Weisbrod

4

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10 February 2020

publication date

19 August 2010

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10 February 2020

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10 February 2020

volume

107

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10 February 2020

page(s)

975-983

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10 February 2020

issue

8

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NADPH oxidases are responsible for the failure of nitric oxide to inhibit migration of smooth muscle cells exposed to high glucose.

10 February 2020

cites work

1 reference

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Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells

28 May 2018

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Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats

28 May 2018

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Identification of structural elements in Nox1 and Nox4 controlling localization and activity.

28 May 2018

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Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2.

28 May 2018

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NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3.

28 May 2018

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Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

28 May 2018

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Cysteine-674 oxidation and degradation of sarcoplasmic reticulum Ca(2+) ATPase in diabetic pig aorta

28 May 2018

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Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

28 May 2018

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Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis

28 May 2018

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High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration

28 May 2018

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Understanding the role of transforming growth factor-beta1 in intimal thickening after vascular injury

28 May 2018

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NOX2 and NOX4 mediate proliferative response in endothelial cells.

28 May 2018

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Alleviation of hepatic steatosis accompanied by modulation of plasma and liver TNF-alpha levels by Trigonella foenum graecum (fenugreek) seeds in Zucker obese (fa/fa) rats

28 May 2018

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Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome

28 May 2018

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

28 May 2018

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Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

28 May 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

28 May 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

28 May 2018

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Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP- or substrate-binding sites of the TGF beta type I receptor kinase

28 May 2018

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Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

28 May 2018

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Structural basis of Smad2 recognition by the Smad anchor for receptor activation

28 May 2018

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

28 May 2018

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Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts

28 May 2018

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Insulin attenuation of vasopressin-induced calcium responses in arterial smooth muscle from Zucker rats

28 May 2018

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Insulin resistance vs. hyperinsulinemia in hypertension: insulin regulation of Ca2+ transport and Ca(2+)-regulation of insulin sensitivity

28 May 2018

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28 May 2018

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A large accumulation of non-muscle myosin occurs at first entry into M phase in rat vascular smooth-muscle cells

28 May 2018

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Resistance to the nitric oxide/cyclic guanosine 5'-monophosphate/protein kinase G pathway in vascular smooth muscle cells from the obese Zucker rat, a classical animal model of insulin resistance: role of oxidative stress.

16 August 2018

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16 August 2018

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16 August 2018

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Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

16 August 2018

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Increased aortic stiffness in the insulin-resistant Zucker fa/fa rat.

16 August 2018

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Expression and localization of NOX2 and NOX4 in primary human endothelial cells

16 August 2018

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The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle

16 August 2018

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Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury

16 August 2018

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Reduced sarco/endoplasmic reticulum Ca(2+) uptake activity can account for the reduced response to NO, but not sodium nitroprusside, in hypercholesterolemic rabbit aorta

16 August 2018

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Cysteine-674 of the sarco/endoplasmic reticulum calcium ATPase is required for the inhibition of cell migration by nitric oxide

16 August 2018

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12 December 2020

Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: a controlled study

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12 December 2020

Hyperinsulinemia and smooth muscle cell proliferation

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12 December 2020

Restenosis rates in diabetic patients: a comparison of coronary stenting and balloon angioplasty in native coronary vessels

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12 December 2020

Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement

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12 December 2020

10.1161/CIRCRESAHA.110.221242

Identifiers

DOI

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10 February 2020

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10 February 2020

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