Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome (Q42413451)

30 October 2017

Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome (English)

1 reference

30 October 2017

P Clint Spiegel

1

1 reference

30 October 2017

Dmitri N Ermolenko

series ordinal

2

1 reference

30 October 2017

Harry F Noller

series ordinal

3

1 reference

30 October 2017

language of work or name

English

0 references

publication date

13 July 2007

1 reference

30 October 2017

1 reference

30 October 2017

13

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30 October 2017

9

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30 October 2017

1473-1482

1 reference

Kinetically competent intermediates in the translocation step of protein synthesis

30 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Identification of two distinct hybrid state intermediates on the ribosome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Tandemly activated tRNAs as participants in protein synthesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

The hybrid state of tRNA binding is an authentic translation elongation intermediate

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Destabilization of the P site codon-anticodon helix results from movement of tRNA into the P/E hybrid state within the ribosome.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Measurement of internal movements within the 30 S ribosomal subunit using Förster resonance energy transfer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Locking and unlocking of ribosomal motions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Mechanism of elongation factor G function in tRNA translocation on the ribosome.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Orientation of ribosome recycling factor in the ribosome from directed hydroxyl radical probing.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

A ratchet-like inter-subunit reorganization of the ribosome during translocation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

EF-G-catalyzed translocation of anticodon stem-loop analogs of transfer RNA in the ribosome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

A complex profile of protein elongation: translating chemical energy into molecular movement

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Thiostrepton: a ribosomal inhibitor of translocation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Ribosomal translocation: facts and models

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Intermediate states in the movement of transfer RNA in the ribosome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Polypeptide-chain elongation promoted by guanyl-5'-yl imidodiphosphate

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Ribosomal translocation promoted by guanylylimido diphosphate and guanylyl-methylene diphosphonate

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

68 Elongation factor G-promoted translocation and polypeptide elongation in ribosomes without GTP cleavage: Use of columns with matrix-bound polyuridylic acid

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Peptidyl-tRNA regulates the GTPase activity of translation factors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Catalysis of ribosomal translocation by sparsomycin

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Initiation factor IF2, thiostrepton and micrococcin prevent the binding of elongation factor G to the Escherichia coli ribosome

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Accurate translocation of mRNA by the ribosome requires a peptidyl group or its analog on the tRNA moving into the 30S P site.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Conformational changes in the ribosome induced by translational miscoding agents.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

The role of guanosine triphosphate in translocation reaction catalyzed by elongation factor G.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950763

A Model of the Functioning Ribosome: Locking and Unlocking of the Ribosome Subparticles

16 August 2018

1 reference

12 December 2020

Studies on translocation. IV. The hydrolysis of a single round of guanosine triphosphate in the presence of fusidic acid

1 reference

12 December 2020

Formation of a complex between GTP, G factor, and ribosomes as an intermediate of ribosome-dependent GTPase reaction

1 reference

12 December 2020

Translocation in ribosomes by attachment-detachment of elongation factor G without GTP cleavage: Evidence from a column-bound ribosome system

1 reference

12 December 2020

Binding interactions between radiolabeled Escherichia coli elongation factor G and the ribosome

1 reference

12 December 2020

The conformational properties of elongation factor G and the mechanism of translocation

1 reference

12 December 2020

Effect of buffer conditions on the position of tRNA on the 70 S ribosome as visualized by cryoelectron microscopy

1 reference

12 December 2020

Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome

1 reference

12 December 2020

Identifiers

DOI

10.1261/RNA.601507

1 reference

30 October 2017

1 reference

30 October 2017

PubMed publication ID

17630323

1 reference