Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice (Q42440126)

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scientific article published on April 21, 2003

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English	Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice	scientific article published on April 21, 2003

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scholarly article

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Europe PubMed Central

31 October 2017

Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice (English)

1 reference

Europe PubMed Central

31 October 2017

Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice (English)

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10.1074/JBC.M300636200

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26 December 2023

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10.1074/JBC.M300636200

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author name string

Bing Zheng

2

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Xu Shi-wen

4

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Ivan Fisher

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Konstantinos Lazaridis

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Benoit de Crombrugghe

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Christopher P. Denton

1

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Lowri A. Evans

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Voon H. Ong

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David J. Abraham

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Carol M. Black

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21 April 2003

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https://api.elsevier.com/content/article/PII:S0021925820869762?httpAccept=text/plain

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https://syndication.highwire.org/content/doi/10.1074/jbc.M300636200

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Journal of Biological Chemistry

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278

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25109-25119

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28

59

2861

author name string

Go

publication date

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1 reference

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10.1074/JBC.M300636200

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American Journal of Physiology

40

284

G525

author name string

Schramm

publication date

2003

1 reference

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10.1074/JBC.M300636200

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

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