STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis (Q42452343)

31 October 2017

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis (English)

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31 October 2017

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Sean M Davidson

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author name string

Paul A Townsend

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31 October 2017

Tiziano M Scarabelli

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31 October 2017

Richard A Knight

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31 October 2017

David S Latchman

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31 October 2017

Anastasis Stephanou

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31 October 2017

language of work or name

English

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publication date

5 November 2003

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Journal of Biological Chemistry

31 October 2017

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31 October 2017

279

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31 October 2017

7

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31 October 2017

5811-5820

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How cells respond to interferons

31 October 2017

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Mdm2 promotes the rapid degradation of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1).

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Binding and modulation of p53 by p300/CBP coactivators

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

STAT1 is inactivated by a caspase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302637200

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302637200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302637200

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31 October 2017

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