Restoring AS160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids (Q42459278)

1 November 2017

Restoring AS160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids (English)

1 reference

1 November 2017

1 reference

1 reference

Adrian Chabowski

2

0 references

Arend Bonen

series ordinal

6

object named as

Arend Bonen

1 reference

1 November 2017

3

Jan F C Glatz

1 reference

1 November 2017

5

Joost J F P Luiken

1 reference

1 November 2017

Hakam Alkhateeb

1

1 reference

PubMed ID

19724017

1 November 2017

Brendon Gurd

series ordinal

4

1 reference

1 November 2017

1 September 2009

1 reference

American Journal of Physiology - Endocrinology and Metabolism

1 November 2017

1 reference

1 November 2017

297

1 reference

1 November 2017

5

1 reference

1 November 2017

E1056-66

1 reference

Two phases of palmitate-induced insulin resistance in skeletal muscle: impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity.

1 November 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

IRS1-independent defects define major nodes of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

In obese rat muscle transport of palmitate is increased and is channeled to triacylglycerol storage despite an increase in mitochondrial palmitate oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Intramuscular lipid oxidation and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Skeletal muscle lipid metabolism with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Development of glucose-induced insulin resistance in muscle requires protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

High-fat diet and leptin treatment alter skeletal muscle insulin-stimulated phosphatidylinositol 3-kinase activity and glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMP kinase activation with AICAR further increases fatty acid oxidation and blunts triacylglycerol hydrolysis in contracting rat soleus muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90908.2008

10.1152/AJPENDO.90908.2008

21 January 2018

Identifiers

DOI

1 reference

1 November 2017

1 reference

PubMed ID

19724017