AKT1 provides an essential survival signal required for differentiation and stratification of primary human keratinocytes (Q42491656)

1 November 2017

AKT1 provides an essential survival signal required for differentiation and stratification of primary human keratinocytes (English)

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1 November 2017

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Barry R Thrash

1

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1 November 2017

Craig W Menges

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2

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1 November 2017

Robert H Pierce

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3

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1 November 2017

Dennis J McCance

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4

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1 November 2017

language of work or name

English

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publication date

3 March 2006

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Journal of Biological Chemistry

1 November 2017

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1 November 2017

281

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1 November 2017

17

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1 November 2017

12155-12162

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Getting under the skin of epidermal morphogenesis

1 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

Role of integrins in regulating epidermal adhesion, growth and differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

21 January 2018

Integrins and anoikis

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

Signal transduction pathways controlling the switch between keratinocyte growth and differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

p63 is the molecular switch for initiation of an epithelial stratification program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Human papillomavirus type 16 alters human epithelial cell differentiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

NF-kappaB determines localization and features of cell death in epidermis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512116200

Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Ultrastructural localization of caspase-14 in human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Epidermal differentiation, apoptosis, and senescence: common pathways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Caspase activation in the terminal differentiation of human epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

Phosphatidylinositol 3-Kinase Is a Key Regulator of Early Phase Differentiation in Keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512116200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512116200

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1 November 2017

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