Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival. (Q42493873)

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12 February 2020

title

Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival (English)

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12 February 2020

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7

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12 February 2020

Clemens O. Hanemann

8

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12 February 2020

author name string

S Ammoun

1

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12 February 2020

M C Schmid

2

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12 February 2020

L Zhou

3

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12 February 2020

N Ristic

4

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12 February 2020

E Ercolano

5

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12 February 2020

D A Hilton

6

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12 February 2020

language of work or name

English

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publication date

5 September 2011

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12 February 2020

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12 February 2020

volume

31

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12 February 2020

issue

13

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12 February 2020

page(s)

1710-1722

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ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma

12 February 2020

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Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma

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Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244.

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PTEN, more than the AKT pathway

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ERM proteins and merlin: integrators at the cell cortex

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IGF system in cancer: from bench to clinic

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PTEN contributes to profound PI3K/Akt signaling pathway deregulation in dystrophin-deficient dog muscle

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Actin-rich protrusions and nonlocalized GTPase activation in Merlin-deficient schwannomas

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Differential gene expression between human schwannoma and control Schwann cells.

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Activation of ERK, AKT and JNK signalling pathways in human schwannomas in situ.

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Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1.

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The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner

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Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I

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Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

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Tyr-863 phosphorylation enhances focal adhesion kinase autophosphorylation at Tyr-397.

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

21 January 2018

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FERM control of FAK function: implications for cancer therapy.

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Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex

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Division of labor of Schwann cell integrins during migration on peripheral nerve extracellular matrix ligands.

21 January 2018

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Integrin-regulated FAK-Src signaling in normal and cancer cells

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Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

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Activation of SRC kinase and phosphorylation of signal transducer and activator of transcription-5 are required for decidual transformation of human endometrial stromal cells.

21 January 2018

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Shedding light on Merlin's wizardry

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Calcineurin mediates AKT dephosphorylation in the ischemic rat retina

21 January 2018

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IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells

21 January 2018

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Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L

21 January 2018

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Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

21 January 2018

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

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Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

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Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells

21 January 2018

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Ubiquitination regulates PTEN nuclear import and tumor suppression

21 January 2018

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Reduced apoptosis rates in human schwannomas.

21 January 2018

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IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

21 January 2018

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The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression

21 January 2018

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The insulin-like growth factor system as a treatment target in breast cancer

21 January 2018

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Is the type I insulin-like growth factor receptor a therapeutic target in endometrial cancer?

21 January 2018

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The IGF/IGFBP system in CNS malignancy

21 January 2018

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Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells

21 January 2018

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Identification of calcineurin as a key signal in the extinction of fear memory.

31 March 2020

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Enhanced proliferation and potassium conductance of Schwann cells isolated from NF2 schwannomas can be reduced by quinidine

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21892205%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

1053611898

0 references

1 reference