Inhibition of p38 pathway leads to OA-like changes in a rat animal model (Q42500459)

1 November 2017

Inhibition of p38 pathway leads to OA-like changes in a rat animal model (English)

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1 November 2017

5

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1 November 2017

6

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1 November 2017

Indira Prasadam

1

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1 November 2017

Xinzhan Mao

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2

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1 November 2017

Yanping Wang

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3

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1 November 2017

Wei Shi

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4

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1 November 2017

12 January 2012

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1 November 2017

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1 November 2017

51

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1 November 2017

5

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1 November 2017

813-823

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MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation--divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation.

1 November 2017

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Inhibition of p38 MAPK signaling in chondrocyte cultures results in enhanced osteogenic differentiation of perichondral cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Regulation of SOX9 mRNA in human articular chondrocytes involving p38 MAPK activation and mRNA stabilization.

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Mitogen-activated protein kinases as therapeutic targets in osteoarthritis

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through BMP pathway and a CCAAT box in the proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Blockade of p38 map kinase inhibits complement-induced acute lung injury in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-kappaB pathway

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

p38 MAP kinase inhibitor prevents diastolic dysfunction in rats following HIV gp120 injection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Osteoarthritic cartilage chondrocytes alter subchondral bone osteoblast differentiation via MAPK signalling pathway involving ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

p38 MAP kinase inhibitor reverses stress-induced myocardial dysfunction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

p38 mitogen-activated protein kinase inhibition decreases TNFalpha secretion and protects against left ventricular remodeling in rats with myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Inhibition of p38 MAPK reverses hypoxia-induced pulmonary artery endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKER360

10.1093/RHEUMATOLOGY/KER360

21 January 2018

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DOI

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1 November 2017

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