P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis (Q43214803)

16 November 2017

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis (English)

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16 November 2017

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Kimberly K Brown

1

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16 November 2017

Sandra A Heitmeyer

2

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16 November 2017

Erin B Hookfin

3

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16 November 2017

Lily Hsieh

4

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16 November 2017

Maria Buchalova

5

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16 November 2017

Yetunde O Taiwo

6

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16 November 2017

Michael J Janusz

7

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16 November 2017

4 December 2008

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16 November 2017

Journal of Inflammation

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16 November 2017

5

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16 November 2017

22

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https://scigraph.springernature.com/pub.10.1186/1476-9255-5-22

16 November 2017

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Signaling transduction: target in osteoarthritis

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25 May 2018

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25 May 2018

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25 May 2018

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The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period

25 May 2018

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R-130823, a novel inhibitor of p38 MAPK, ameliorates hyperalgesia and swelling in arthritis models

15 August 2018

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Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis

15 August 2018

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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

15 August 2018

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15 August 2018

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Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial. Evaluation of the Chondromodulating Effect of Diacerein in OA of the Hip.

15 August 2018

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A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

15 August 2018

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Endoneurial injection of TNF-alpha produces neuropathic pain behaviors.

15 August 2018

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Efficacy and safety of diacerein in osteoarthritis of the knee: a double-blind, placebo-controlled trial. The Diacerein Study Group

15 August 2018

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12 December 2020

Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression

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12 December 2020

In vitro effects of diacerhein and rhein on interleukin 1 and tumor necrosis factor-alpha systems in human osteoarthritic synovium and chondrocytes

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12 December 2020

The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

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12 December 2020

Inhibition of p38 mitogen-activated protein kinase attenuates interleukin-1beta-induced thermal hyperalgesia and inducible nitric oxide synthase expression in the spinal cord

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12 December 2020

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

1 reference

12 December 2020

Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function

1 reference

12 December 2020

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

1 reference

12 December 2020

In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes

1 reference

12 December 2020

Diacerhein and rhein reduce the ICE-induced IL-1beta and IL-18 activation in human osteoarthritic cartilage

1 reference

12 December 2020

Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-9255-5-22

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Dimensions Publication ID

16 November 2017

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1 reference

16 November 2017

1 reference