A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production (Q42503419)

1 November 2017

A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production (English)

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1 November 2017

3

Alexandra C Newton

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1 November 2017

Daniel R Dries

1

1 reference

PubMed ID

17071619

1 November 2017

Lisa L Gallegos

series ordinal

2

1 reference

PubMed ID

17071619

1 November 2017

language of work or name

English

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publication date

27 October 2006

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Journal of Biological Chemistry

1 November 2017

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1 November 2017

282

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1 November 2017

2

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1 November 2017

826-830

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The extended protein kinase C superfamily

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

C1 domains exposed: from diacylglycerol binding to protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Subcellular targeting by membrane lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Increased membrane affinity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C betaII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Protein Modeling by E-mail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

SWISS-MODEL: An automated protein homology-modeling server

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

P2Y receptors of MDCK cells: epithelial cell regulation by extracellular nucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Regulation of cell apoptosis by protein kinase c delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

How proteins adapt to a membrane-water interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C600268200

21 January 2018

Identifiers

DOI

10.1074/JBC.C600268200

1 reference

1 November 2017

1 reference

PubMed ID

17071619