Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis (Q42526474)

1 November 2017

Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis (English)

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1 November 2017

1

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1 November 2017

Mohammed Qatanani

2

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1 November 2017

Steven S Chua

3

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1 November 2017

Jennifer L LaRey

4

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1 November 2017

Stacy A Johnson

5

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1 November 2017

Mitsuhiro Watanabe

6

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1 November 2017

David D Moore

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1 November 2017

Yoon Kwang Lee

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1 November 2017

language of work or name

English

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publication date

1 May 2008

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1 November 2017

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1 November 2017

47

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1 November 2017

5

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1 November 2017

1578-1586

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The enzymes, regulation, and genetics of bile acid synthesis

1 November 2017

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Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

21 January 2018

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Identification of a nuclear receptor for bile acids

21 January 2018

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Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

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Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids

21 January 2018

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Redundant pathways for negative feedback regulation of bile acid production

21 January 2018

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Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

21 January 2018

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

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Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

21 January 2018

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Benefit of farnesoid X receptor inhibition in obstructive cholestasis

21 January 2018

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Identification of a hormonal basis for gallbladder filling.

21 January 2018

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Resistance of SHP-null mice to bile acid-induced liver damage

21 January 2018

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Insights into gender bias: rat cytochrome P450 3A9

21 January 2018

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Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation

21 January 2018

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An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

21 January 2018

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The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors

21 January 2018

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Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

21 January 2018

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Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism

21 January 2018

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Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration

21 January 2018

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Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles

21 January 2018

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Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

21 January 2018

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Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.

21 January 2018

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Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

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7 January 2021

Simultaneous determination of bile acids in rat bile and serum by high-performance liquid chromatography

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7 January 2021

Novel receptor interaction and repression domains in the orphan receptor SHP.

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7 January 2021

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

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7 January 2021

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

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7 January 2021

Identifiers

DOI

10.1002/HEP.22196

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1 November 2017

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