Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation. (Q42557662)

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scientific article published on 8 September 2009

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English	Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.	scientific article published on 8 September 2009

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7 February 2020

Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation (English)

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Federico Biscetti

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Giulia De Angelis

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Giuseppe Straface

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Vincenzo Arena

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Egidio Stigliano

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Giovanni Pecorini

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Paola Rizzo

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Giovanni Ghirlanda

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Andrea Flex

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8 September 2009

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Cardiovascular Diabetology

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0 references

Diabetes-related microvascular and macrovascular diseases in the physical therapy setting

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Relationship of glycemic control, exogenous insulin, and C-peptide levels to ischemic heart disease mortality over a 16-year period in people with older-onset diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR).

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Troglitazone and pioglitazone interactions via PPAR-gamma-independent and -dependent pathways in regulating physiological responses in renal tubule-derived cell lines

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Pioglitazone-induced insulin sensitization improves vascular endothelial function in nondiabetic patients with essential hypertension.

1 reference

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Thiazolidinediones inhibit TNFalpha induction of PAI-1 independent of PPARgamma activation

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Abnormal angiogenesis in diabetes mellitus

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Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

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Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists

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28 May 2018

Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications

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Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

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28 May 2018

Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus

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Pioglitazone inhibits homocysteine-induced migration of vascular smooth muscle cells through a peroxisome proliferator-activated receptor gamma-independent mechanism

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Peroxisome proliferator-activated receptor-gamma-agonist, rosiglitazone, promotes angiogenesis after focal cerebral ischemia.

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16 August 2018

Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control: results from the pioneer study

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1 reference

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16 August 2018

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16 August 2018

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16 August 2018

Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistant animals.

1 reference

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16 August 2018

[Glycaemic control and macrovascular complications in patients with diabetes mellitus]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

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The PPAR-gamma agonist pioglitazone increases neoangiogenesis and prevents apoptosis of endothelial progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone ameliorates endothelial dysfunction and restores ischemia-induced angiogenesis in diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt as a therapeutic target in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

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Peroxisome proliferator-activated receptor-gamma agonists increase vascular endothelial growth factor expression in human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelium-dependent relaxation in aorta of BB rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

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Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of experimental diabetes mellitus in rats on glomerular capillary number and sizes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195

1 reference

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Acute effects of hyperglycaemia with and without exercise on endothelial function in healthy young men

1 reference

https://pubmed.ncbi.nlm.nih.gov/19737384

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based on heuristic

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Identifiers

10.1186/1475-2840-8-49

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Europe PubMed Central

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7 February 2020

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1475-2840-8-49

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19737384%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

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7 February 2020

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