Altered hepatic BMP signaling pathway in human HFE hemochromatosis (Q42596912)

3 November 2017

Altered hepatic BMP signaling pathway in human HFE hemochromatosis (English)

1 reference

3 November 2017

3

1 reference

3 November 2017

Antonello Pietrangelo

9

1 reference

3 November 2017

2

Cinzia Garuti

1 reference

3 November 2017

6

Armin Finkenstedt

1 reference

3 November 2017

Giuliano Bolondi

1

1 reference

3 November 2017

Heinz Zoller

4

1 reference

3 November 2017

Wolfgang Vogel

5

1 reference

3 November 2017

Jodie L Babitt

7

1 reference

3 November 2017

Herbert Y Lin

8

1 reference

3 November 2017

21 September 2010

1 reference

Blood Cells, Molecules and Diseases

3 November 2017

1 reference

3 November 2017

45

1 reference

3 November 2017

308-312

1 reference

3 November 2017

4

1 reference

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice

3 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

The RGM/DRAGON family of BMP co-receptors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

A mouse model of juvenile hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Induction and regulation of Smad7 in the gastric mucosa of patients with Helicobacter pylori infection.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Two major Smad pathways in TGF-beta superfamily signalling.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Global prevalence of putative haemochromatosis mutations

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Hepcidin is decreased in TFR2 hemochromatosis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295241

Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20863724

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCMD.2010.08.010

1 reference

3 November 2017

1 reference

3 November 2017

1 reference