The rationale and design of TransCon Growth Hormone for the treatment of growth hormone deficiency (Q42635183)

4 November 2017

The rationale and design of TransCon Growth Hormone for the treatment of growth hormone deficiency (English)

1 reference

4 November 2017

Kennett Sprogøe

1

1 reference

4 November 2017

Eva Mortensen

series ordinal

2

1 reference

4 November 2017

David B Karpf

series ordinal

3

1 reference

4 November 2017

Jonathan A Leff

series ordinal

4

1 reference

4 November 2017

25 September 2017

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4 November 2017

Endocrine Connections

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4 November 2017

6

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4 November 2017

R171-R181

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4 November 2017

8

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Creative Commons Attribution 4.0 International

4 November 2017

start time

1 November 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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MOD-4023, a long-acting carboxy-terminal peptide-modified human growth hormone: results of a Phase 2 study in growth hormone-deficient adults

27 May 2018

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Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations

27 May 2018

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PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs

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A Randomized Safety and Efficacy Study of Somavaratan (VRS-317), a Long-Acting rhGH, in Pediatric Growth Hormone Deficiency

27 May 2018

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A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins.

27 May 2018

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PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development

27 May 2018

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27 May 2018

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GH and the cardiovascular system: an update on a topic at heart

27 May 2018

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Novel PEGylated basal insulin LY2605541 has a preferential hepatic effect on glucose metabolism

27 May 2018

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Adult growth hormone deficiency - benefits, side effects, and risks of growth hormone replacement

27 May 2018

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Developing long-acting growth hormone formulations.

27 May 2018

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Growth hormone therapy with norditropin ( somatropin ) in growth hormone deficiency

27 May 2018

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Understanding the growth hormone therapy adherence paradigm: a systematic review

27 May 2018

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Body composition and quality of life in adults treated with GH therapy: a systematic review and meta-analysis

27 May 2018

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Non-compliance with growth hormone treatment in children is common and impairs linear growth

27 May 2018

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Acromegaly pathogenesis and treatment

27 May 2018

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Insulin-like growth factor-I (rhIGF-I) therapy of short stature

27 May 2018

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The role of recombinant human insulin-like growth factor-I in treating children with short stature

27 May 2018

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The somatomedin hypothesis 2007: 50 years later

27 May 2018

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Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1.

27 May 2018

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In vivo delivery of fluoresceinated dextrans to the murine growth plate: imaging of three vascular routes by multiphoton microscopy

27 May 2018

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Pharmacokinetics of pegylated interferons: what is misleading?

27 May 2018

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The heart: an end-organ of GH action

27 May 2018

1 reference

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A multicenter study of the efficacy and safety of sustained release GH in the treatment of naive pediatric patients with GH deficiency

27 May 2018

1 reference

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Long-term effects of continuous subcutaneous infusion versus daily subcutaneous injections of growth hormone (GH) on the insulin-like growth factor system, insulin sensitivity, body composition, and bone and lipoprotein metabolism in GH-deficient ad

27 May 2018

1 reference

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Four decades of growth hormone therapy for short children: what have we achieved?

27 May 2018

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Conserved and unique amino acid residues in the domains of the growth hormones. Flounder growth hormone deduced from the cDNA sequence has the minimal size in the growth hormone prolactin gene family

27 May 2018

1 reference

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Use of growth hormone-gel

27 May 2018

1 reference

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Long-Acting C-Terminal Peptide-Modified hGH (MOD-4023): Results of a Safety and Dose-Finding Study in GHD Children.

27 May 2018

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A Randomized Phase 2 Study of Long-Acting TransCon GH vs Daily GH in Childhood GH Deficiency

16 August 2018

1 reference

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Attaining genetic height potential: Analysis of height outcomes from the ANSWER Program in children treated with growth hormone over 5 years.

16 August 2018

1 reference

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24-month use of once-weekly GH, LB03002, in prepubertal children with GH deficiency.

16 August 2018

1 reference

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Three-year efficacy and safety of LB03002, a once-weekly sustained-release growth hormone (GH) preparation, in prepubertal children with GH deficiency (GHD).

16 August 2018

1 reference

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Compliance and persistence in pediatric and adult patients receiving growth hormone therapy

16 August 2018

1 reference

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Long-term IGF-I treatment of children with Laron syndrome increases adiposity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5655688

A long-acting human growth hormone (Nutropin Depot): efficacy and safety following two years of treatment in children with growth hormone deficiency

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5655688

Supraphysiological doses of GH induce rapid changes in cardiac morphology and function.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5655688

Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: effects on circulating insulin-like growth factor-I and metabolic indices

16 August 2018

1 reference

12 December 2020

Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency

1 reference

12 December 2020

A reversible albumin-binding growth hormone derivative is well tolerated and possesses a potential once-weekly treatment profile

1 reference

12 December 2020

Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH

1 reference

12 December 2020

Pegylated Long-Acting Human Growth Hormone Possesses a Promising Once-Weekly Treatment Profile, and Multiple Dosing Is Well Tolerated in Adult Patients with Growth Hormone Deficiency

1 reference

12 December 2020

Long-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice

1 reference

12 December 2020

Increased prevalence of regurgitant valvular heart disease in acromegaly

1 reference

12 December 2020

Differential regulation of serum growth hormone (GH)-binding protein during continuous infusion versus daily injection of recombinant human GH in GH-deficient children

1 reference

12 December 2020

Effects on metabolic variables after 12-month treatment with a new once-a-week sustained-release recombinant growth hormone (GH: LB03002) in patients with GH deficiency

1 reference

12 December 2020

Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity

1 reference

12 December 2020

Identifiers

DOI

10.1530/EC-17-0203

1 reference

4 November 2017

1 reference

4 November 2017

1 reference