Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens (Q42716358)

5 November 2017

Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens (English)

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5 November 2017

Elsie Diaz

1

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5 November 2017

Carl A Machutta

2

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5 November 2017

Stephanie Chen

3

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5 November 2017

Yong Jiang

4

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5 November 2017

Christopher Nixon

5

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5 November 2017

Glenn Hofmann

6

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5 November 2017

Danielle Key

7

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5 November 2017

Sharon Sweitzer

8

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5 November 2017

Mehul Patel

9

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5 November 2017

Zining Wu

10

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5 November 2017

Caretha L Creasy

11

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5 November 2017

Ryan G Kruger

12

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5 November 2017

Louis LaFrance

13

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5 November 2017

Sharad K Verma

14

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5 November 2017

Melissa B Pappalardi

15

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5 November 2017

Baochau Le

16

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5 November 2017

Glenn S Van Aller

17

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5 November 2017

Michael T McCabe

18

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5 November 2017

Peter J Tummino

19

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5 November 2017

Andrew J Pope

20

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5 November 2017

Sara H Thrall

21

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5 November 2017

Benjamin Schwartz

22

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5 November 2017

Martin Brandt

23

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5 November 2017

17 August 2012

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Journal of Biomolecular Screening

5 November 2017

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5 November 2017

17

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5 November 2017

10

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5 November 2017

1279-1292

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An operational definition of epigenetics

5 November 2017

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https://api.crossref.org/works/10.1177%2F1087057112453765

Chromatin structure and the inheritance of epigenetic information

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Histone methyltransferases in cancer

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

The diverse functions of histone lysine methylation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Histone lysine methylation: an epigenetic modification?

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

The Polycomb complex PRC2 and its mark in life

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Clinical significance of Polycomb gene expression in brain tumors.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

A fast and efficient method for quantitative measurement of S-adenosyl-L-methionine-dependent methyltransferase activity with protein substrates

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Scintillation proximity assays in high-throughput screening

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Process validation and screen reproducibility in high-throughput screening.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Statistics and decision making in high-throughput screening.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Assay development and high-throughput screening of small molecular c-Abl kinase activators

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Thousands of chemical starting points for antimalarial lead identification

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Role of the polycomb protein EED in the propagation of repressive histone marks

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

A simplified scintillation proximity assay for fatty acid synthase activity: development and comparison with other FAS activity assays

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

High throughput characterization of combinatorial histone codes

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Structure and catalytic mechanism of the human histone methyltransferase SET7/9

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057112453765

Structural origins for the product specificity of SET domain protein methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

A Continuous Protein Methyltransferase (G9a) Assay for Enzyme Activity Measurement and Inhibitor Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057112453765

21 January 2018

Identifiers

DOI

10.1177/1087057112453765

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5 November 2017

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