Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation (Q42722612)

5 November 2017

title

Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation (English)

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5 November 2017

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7

Michael P Manns

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5 November 2017

Ursula Ehmer

1

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5 November 2017

Sandra Kalthoff

2

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Bastian Fakundiny

3

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5 November 2017

Brigitte Pabst

4

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Nicole Freiberg

5

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5 November 2017

Ronald Naumann

6

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Christian P Strassburg

8

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5 November 2017

language of work or name

English

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publication date

23 April 2012

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5 November 2017

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5 November 2017

volume

55

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5 November 2017

issue

6

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5 November 2017

page(s)

1912-1921

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Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?

5 November 2017

cites work

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The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

21 January 2018

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Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

21 January 2018

1 reference

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

21 January 2018

1 reference

Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk

21 January 2018

1 reference

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

21 January 2018

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Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects

21 January 2018

1 reference

Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids

21 January 2018

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Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10.

21 January 2018

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Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene.

21 January 2018

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Identification and characterization of a functional TATA box polymorphism of the UDP glucuronosyltransferase 1A7 gene

21 January 2018

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Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment

21 January 2018

1 reference

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer

21 January 2018

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UDP-glucuronosyltransferase activity in human liver and colon

21 January 2018

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Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

21 January 2018

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Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population

21 January 2018

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Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene

21 January 2018

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Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

21 January 2018

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Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

21 January 2018

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SLCO1B1 variants and statin-induced myopathy--a genomewide study

21 January 2018

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The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

21 January 2018

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Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization

21 January 2018

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Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.

21 January 2018

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Genetic variability of aryl hydrocarbon receptor (AhR)-mediated regulation of the human UDP glucuronosyltransferase (UGT) 1A4 gene

21 January 2018

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Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

21 January 2018

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The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

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Combined effect of regulatory polymorphisms on transcription of UGT1A1 as a cause of Gilbert syndrome

21 January 2018

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UGT1A1 genotypes and glucuronidation of SN-38, the active metabolite of irinotecan

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype

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inferred from DOI database lookup

7 January 2021

based on heuristic

Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A)

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.25561

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5 November 2017

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