Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding (Q42722712)

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scientific article published on 15 March 2011

Language	Label	Description	Also known as
English	Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding	scientific article published on 15 March 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding (English)

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

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Christoph Garbers

1

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Friedrich Koch-Nolte

7

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Nathalie Jänner

2

object named as

Nathalie Jänner

0 references

Stefan Rose-John

object named as

Stefan Rose-John

8

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author name string

Nathalie Jänner

2

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Athena Chalaris

3

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Marcia L Moss

4

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Doreen M Floss

5

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Dörte Meyer

6

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Jürgen Scheller

9

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

language of work or name

0 references

publication date

15 March 2011

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

286

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

17

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

14804-14811

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

The soluble Interleukin 6 receptor: generation and role in inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Autocrine IL-6 signaling: a key event in tumorigenesis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

The IL-6/sIL-6R complex as a novel target for therapeutic approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

ADAMs: key components in EGFR signalling and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

The ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine-rich domains 2 and 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Altered cytokine production in mice lacking P2X(7) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Shedding of the soluble IL-6 receptor is triggered by Ca2+ mobilization, while basal release is predominantly the product of differential mRNA splicing in THP-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Soluble receptors for cytokines and growth factors: generation and biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

27 May 2018

Differences in wound healing in mice with deficiency of IL-6 versus IL-6 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

16 August 2018

Activation of the P2X7 ion channel by soluble and covalently bound ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

16 August 2018

Adenosine triphosphate-induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083187

16 August 2018

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.229393

21 January 2018

Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.229393

21 January 2018

An essential role for ectodomain shedding in mammalian development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commons category

Species specificity

0 references

Identifiers

10.1074/JBC.M111.229393

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

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commonswiki Category:Species specificity

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