Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection (Q42736812)

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scientific article published on 9 May 2014

Language	Label	Description	Also known as
English	Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection	scientific article published on 9 May 2014

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scholarly article

1 reference

Europe PubMed Central

6 November 2017

Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection (English)

1 reference

Europe PubMed Central

6 November 2017

Randy J. Seeley

10

1 reference

Europe PubMed Central

6 November 2017

Daniel J. Drucker

11

object named as

Daniel J Drucker

1 reference

Europe PubMed Central

6 November 2017

Erin E Mulvihill

4

object named as

Erin E Mulvihill

1 reference

Europe PubMed Central

6 November 2017

author name string

John R Ussher

1

1 reference

Europe PubMed Central

6 November 2017

Laurie L Baggio

2

1 reference

Europe PubMed Central

6 November 2017

Jonathan E Campbell

3

1 reference

Europe PubMed Central

6 November 2017

Minsuk Kim

5

1 reference

Europe PubMed Central

6 November 2017

M Golam Kabir

6

1 reference

Europe PubMed Central

6 November 2017

Xiemin Cao

7

1 reference

Europe PubMed Central

6 November 2017

Benjamin M Baranek

8

1 reference

Europe PubMed Central

6 November 2017

Doris A Stoffers

9

1 reference

Europe PubMed Central

6 November 2017

publication date

9 May 2014

1 reference

Europe PubMed Central

6 November 2017

Molecular Metabolism

1 reference

Europe PubMed Central

6 November 2017

3

1 reference

Europe PubMed Central

6 November 2017

507-517

1 reference

Europe PubMed Central

6 November 2017

5

1 reference

Europe PubMed Central

6 November 2017

Impact of acute hyperglycemia on myocardial infarct size, area at risk, and salvage in patients with STEMI and the association with exenatide treatment: results from a randomized study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

GLP-1 at physiological concentrations recruits skeletal and cardiac muscle microvasculature in healthy humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Molecular mechanisms of diabetic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Identification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model

1 reference

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Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus

1 reference

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Pharmacology, physiology, and mechanisms of incretin hormone action

1 reference

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GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure

1 reference

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27 May 2018

Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies

1 reference

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Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency

1 reference

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27 May 2018

A glucagon-like peptide-1 analog reverses the molecular pathology and cardiac dysfunction of a mouse model of obesity

1 reference

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27 May 2018

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.

1 reference

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27 May 2018

Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism

1 reference

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27 May 2018

Cardiovascular biology of the incretin system

1 reference

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27 May 2018

The effect of glucagon-like peptide 1 on cardiovascular risk

1 reference

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27 May 2018

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

1 reference

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27 May 2018

Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency

1 reference

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27 May 2018

Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons.

1 reference

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27 May 2018

Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance

1 reference

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27 May 2018

Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice

1 reference

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27 May 2018

Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Clinical review: The extrapancreatic effects of glucagon-like peptide-1 and related peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Effects of intensive glucose lowering in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

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Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure

1 reference

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Cardiac function in mice lacking the glucagon-like peptide-1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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27 May 2018

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

1 reference

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27 May 2018

Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

27 May 2018

Postprandial alterations in hemodynamics and blood pressure in normal subjects

1 reference

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27 May 2018

Long-term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

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Cardioprotective effects of exenatide in patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention: results of exenatide myocardial protection in revascularization study.

1 reference

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Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: the EXAMI study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

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Exenatide alters myocardial glucose transport and uptake depending on insulin resistance and increases myocardial blood flow in patients with type 2 diabetes.

1 reference

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Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety.

1 reference

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Glucagon-like peptide-1 (GLP-1) attenuates post-resuscitation myocardial microcirculatory dysfunction

1 reference

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Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

16 August 2018

Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4099509

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Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials

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Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin.

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Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy

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16 August 2018

Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury

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Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy

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16 August 2018

Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion

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Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid retention with thiazolidinediones: does the mechanism influence the outcome?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLMET.2014.04.009

1 reference

Europe PubMed Central

6 November 2017

1 reference

Europe PubMed Central

6 November 2017

1 reference

Europe PubMed Central

6 November 2017

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