Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2. (Q42748422)

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scientific article published on 25 July 2008

Language	Label	Description	Also known as
English	Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2.	scientific article published on 25 July 2008

Statements

scholarly article

1 reference

Europe PubMed Central

6 November 2017

Substrates and non-transportable analogues induce structural rearrangements at the extracellular entrance of the glial glutamate transporter GLT-1/EAAT2. (English)

1 reference

Europe PubMed Central

6 November 2017

author name string

Shaogang Qu

1

1 reference

Europe PubMed Central

6 November 2017

Baruch I Kanner

2

1 reference

Europe PubMed Central

6 November 2017

language of work or name

0 references

publication date

25 July 2008

1 reference

Europe PubMed Central

6 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

6 November 2017

283

1 reference

Europe PubMed Central

6 November 2017

26391-26400

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Europe PubMed Central

6 November 2017

39

1 reference

Europe PubMed Central

6 November 2017

Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Structure of a glutamate transporter homologue from Pyrococcus horikoshii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Molecular determinant of ion selectivity of a (Na+ + K+)-coupled rat brain glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Flux coupling in a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Adjacent pore-lining residues within sodium channels identified by paired cysteine mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Structure of the sodium channel pore revealed by serial cysteine mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Identification of tryptophan residues critical for the function and targeting of the gamma-aminobutyric acid transporter (subtype A).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Binding order of substrates to the (sodium + potassium ion)-coupled L-glutamic acid transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Structural Aspects of Metal Liganding to Functional Groups in Proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Cloning and expression of a rat brain L-glutamate transporter

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

27 May 2018

Active transport of L-glutamate by membrane vesicles isolated from rat brain

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27 May 2018

Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Cysteine-scanning mutagenesis reveals a conformationally sensitive reentrant pore-loop in the glutamate transporter GLT-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Proximity of two oppositely oriented reentrant loops in the glutamate transporter GLT-1 identified by paired cysteine mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Coupled, but not uncoupled, fluxes in a neuronal glutamate transporter can be activated by lithium ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Biotinylation of single cysteine mutants of the glutamate transporter GLT-1 from rat brain reveals its unusual topology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Kinetics of a human glutamate transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2546532

16 August 2018

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802401200

21 January 2018

The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate 404 is involved in the substrate discrimination of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural rearrangements at the translocation pore of the human glutamate transporter, EAAT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18658151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M802401200

1 reference

Europe PubMed Central

6 November 2017

1 reference

Europe PubMed Central

6 November 2017

1 reference

Europe PubMed Central

6 November 2017

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