Conformational differences between surface-bound and fluid-phase complement-component-C3 fragments. Epitope mapping by cDNA expression (Q42793066)

7 November 2017

Conformational differences between surface-bound and fluid-phase complement-component-C3 fragments. Epitope mapping by cDNA expression (English)

1 reference

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19 September 2022

1

Nilsson B

1 reference

7 November 2017

7

J. D. Lambris

1 reference

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19 September 2022

author name string

D. Grossberger

2

1 reference

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19 September 2022

K. Nilsson Ekdahl

3

1 reference

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19 September 2022

P. Riegert

4

1 reference

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19 September 2022

D. J. Becherer

5

1 reference

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19 September 2022

U. R. Nilsson

6

1 reference

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19 September 2022

language of work or name

English

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publication date

1 March 1992

1 reference

PMCID

1130846

7 November 2017

15 March 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1372802

full work available at URL

19 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1372802/pdf/?tool=EBI

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Portable Document Format

online access status

open access

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1372802/?tool=EBI

19 September 2022

1 reference

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https://europepmc.org/articles/PMC1130846

19 September 2022

1 reference

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https://europepmc.org/articles/PMC1130846?pdf=render

19 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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19 September 2022

1 reference

7 November 2017

282 ( Pt 3)

1 reference

7 November 2017

715-721

1 reference

The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum

7 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Covalent binding and hemolytic activity of complement proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Mapping of the properdin-binding site in the third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Generation of three different fragments of bound C3 with purified factor I or serum. I. Requirements for factor H vs CR1 cofactor activity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Method to map antigenic determinants recognized by monoclonal antibodies: localization of a determinant of virus neutralization on the feline leukemia virus envelope protein gp70

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Detection of disulphide bonds and localization of interchain linkages in the third (C3) and the fourth (C4) components of human complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Molecular modelling of human complement component C3 and its fragments by solution scattering.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Membrane complement receptors specific for bound fragments of C3.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

The multifunctional role of C3, the third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Identification of the C3b receptor-binding domain in third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

A new and fast method for preparing high quality lambda DNA suitable for sequencing

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Minipreps of DNA from bacteriophage lambda

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Conservation of structural and functional domains in complement component C3 of Xenopus and mammals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Human complement component C3: cDNA coding sequence and derived primary structure

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Antigens of complement factor C3 involved in the interactions with factors I and H.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Molecular aspects of C3 interactions and structural/functional analysis of C3 from different species.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies on the specificity of factor I

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Structural and Functional Analysis of C3 Using Monoclonal Antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Preparative and analytical purification of DNA from agarose

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Physico-chemical and antigenic properties of human C3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1130846

Location of the inter-chain disulfide bonds of the third component of human complement

27 May 2018

1 reference

12 December 2020

Altered antigenic expressions of human C3 and C5, their subunits and fragments following exposure to denaturing conditions

1 reference

12 December 2020

The structure and function of the third component of human complement—I. The nature and extent of conformational changes accompanying C3 activation

1 reference

12 December 2020

An assessment of the extent of antigenic analogy between physiologically bound C3 and C3 denatured by sodium dodecyl sulphate

1 reference

12 December 2020

Production of mouse monoclonal antibodies that detect distinct neoantigenic epitopes on bound C3b and iC3b but not on the corresponding soluble fragments

1 reference

12 December 2020

The C terminus of the anaphylatoxin C3a generated upon complement activation represents a neoantigenic determinant with diagnostic potential

1 reference

12 December 2020

Distinctive expression of neoantigenic C3(D) epitopes on bound C3 following activation and binding to different target surfaces in normal and pathological human sera

1 reference

12 December 2020

Characterization of tryptic fragments of human complement factor C3

1 reference

12 December 2020

Analogous antigenic alterations elicited in C3 by physiologic binding and by denaturation in the presence of sodium dodecylsulfate

1 reference

12 December 2020

Conformational changes accompanying proteolytic cleavage of human complement protein C3b by the regulatory enzyme factor I and its cofactor H. Spectroscopic and enzymological studies

1 reference

12 December 2020

Simplified assays of hemolytic activity of the classical and alternative complement pathways

1 reference

12 December 2020

Large scale isolation of functionally active components of the human complement system

1 reference

12 December 2020

Human C3 and C5: subunit structure and modifications by trypsin and C42-C423

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2820715

1 reference

7 November 2017

1 reference

7 November 2017

1 reference

PMCID

1130846