Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover (Q42796363)

7 November 2017

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover (English)

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7 November 2017

Henderson BR

1

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7 November 2017

1 September 2000

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7 November 2017

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7 November 2017

2

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7 November 2017

653-660

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7 November 2017

9

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https://scigraph.springernature.com/pub.10.1038/35023605

7 November 2017

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cites work

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients

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7 January 2021

Lessons from hereditary colorectal cancer

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7 January 2021

Analysis of masked mutations in familial adenomatous polyposis

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7 January 2021

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

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7 January 2021

APC: the plot thickens

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7 January 2021

Association of the APC gene product with beta-catenin

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7 January 2021

Association of the APC tumor suppressor protein with catenins

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7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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7 January 2021

Carcinogenesis: a balance between beta-catenin and APC.

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7 January 2021

beta-catenin signaling and cancer

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7 January 2021

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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7 January 2021

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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Identification of c-MYC as a target of the APC pathway

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7 January 2021

Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.

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7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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7 January 2021

Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells

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7 January 2021

Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.

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7 January 2021

Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells

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7 January 2021

The APC protein binds to A/T rich DNA sequences

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7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

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7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

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7 January 2021

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export

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7 January 2021

Evidence for a role of CRM1 in signal-mediated nuclear protein export

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7 January 2021

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

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7 January 2021

Transport into and out of the cell nucleus

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7 January 2021

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

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7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

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7 January 2021

Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

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Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

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7 January 2021

Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor

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7 January 2021

Dimer formation by an N-terminal coiled coil in the APC protein

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7 January 2021

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

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7 January 2021

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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7 January 2021

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

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7 January 2021

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

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7 January 2021

Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression

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7 January 2021

Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin

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7 January 2021

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

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7 January 2021

beta-catenin can be transported into the nucleus in a Ran-unassisted manner

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7 January 2021

Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression

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7 January 2021

Identifiers

DOI

10.1038/35023605

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7 November 2017

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PubMed ID

10980707